Current Clinical Studies | Mood Disorders Research Program | Department of Psychiatry and Behavioral Sciences | UC Davis Health

Description
The TRANSCEND Study is a clinical study for people with depression who have been unable to find relief from their symptoms after trying at least four different antidepressant treatments. The goal of the study is to evaluate the safety and effectiveness of deep brain stimulation (DBS) as an investigational therapy to treat treatment resistant depression (TRD) using the Infinity DBS System.

DBS involves a surgical procedure during which electrodes are placed in the brain. The DBS electrodes will stimulate an area in the brain thought to help reduce the symptoms of depression. 

Recruitment Period
Recruitment period is currently open.

Ages
22-70 years

Keywords
Depression, major depression, deep brain stimulation, major depressive disorder, MDD, treatment resistant depression

James Bourgeois, O.D., M.P.A., M.D.
Co-Principal Investigator

Description
We are doing a research study to see if a treatment called Transcranial Magnetic Stimulation (TMS) can help people who feel depressed and have had thoughts of suicide. TMS sends magnetic pulses to the brain to help improve mood. Study volunteers will get this treatment for 5 days and come back for a few check-ins over about 5 weeks. 

Recruitment Period
Recruitment period is currently open and we are offering compensation.

Ages
15-21 years

Keywords
depression, mood, suicidal thoughts, mental health, TMS

Se Ri (Sally) Bae, M.D., Resident, Psychiatry and Behavioral Sciences
Investigator

Description
We are doing research to better understand aggressive behavior in children and teens. Right now, there isn’t a clear diagnosis for this kind of behavior, even though it affects many families. We’re testing a short questionnaire to see how well it help doctors learn about aggression and find better ways to treat it. By joining this study, you can your child can help researchers improve care for other families facing similar challenges. 

Recruitment Period
Recruitment period is currently open and we are offering compensation.

Ages
4-12 years

Keywords
child, behavior, disruptive behavior, aggression

Emma Hare, D.O., Child and Adolescent Psychiatry Fellow
Investigator