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Keith Baar, Ph.D. for UC Davis Health

Keith  Baar, Ph.D.

Keith Baar, Ph.D.

Professor

Specialties

Sports Medicine

Locations and Contact

UC Davis Medical Center

UC Davis Medical Center
2315 Stockton Blvd.
Sacramento, CA 95817

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Research/Academic Interests

Dr. Baar is a molecular exercise physiologist who studies how musculoskeletal (muscle, tendon, and ligament) performance is affected by exercise, nutrition, age, and disease using a series of culture, animal and human models. Dr. Baar is ranked by Expertscape (an independent website ranking scientific publications) in the top 0.01% worldwide for Skeletal Muscle Researchers.

Undergraduate School

B.S., University of Michigan, Ann Arbor MI 1992

Other School

M.A., Physiology, UC Berkeley, Berkeley CA 1994

Other School

Ph.D., Physiology, University of Illinois, Chicago IL 2000

Fellowship

Gerontology, University of Michigan, Ann Arbor MI 2001-2004

Fellowship

Gerontology, Washington University, St. Louis IL 2000-2021

Hellman Fellow, 2011

Nominated for the Associated Students of the University of California, 2011

Fellow, The American College of Sports Medicine, 2008

Pfizer Prize Lecture, Physiological Society, London, 2004

Award for Outstanding Research Mentorship, 2003

Wallace MA, Aguirre NW, Marcotte GR, Marshall AG, Baehr LM, Hughes DC, Hamilton KL, Roberts MN, Lopez-Dominguez JA, Miller BF, Ramsey JJ, Baar K. The ketogenic diet preserves skeletal muscle with aging in mice. Aging Cell. 2021 Apr;20(4):e13322. doi:10.1111/acel.13322. Epub 2021 Mar 6. PMID:33675103.

Baar K. Stress Relaxation and Targeted Nutrition to Treat Patellar Tendinopathy. Int J Sport Nutr Exerc Metab. 2019 Jul 1;29(4):453–457. doi:10.1123/ijsnem.2018-0231. PMID:30299199.

Roberts MN, Wallace MA, Tomilov AA, Zhou Z, Marcotte GR, Tran D, Perez G, Gutierrez-Casado E, Koike S, Knotts TA, Imai DM, Griffey SM, Kim K, Hagopian K, McMackin MZ, Haj FG, Baar K, Cortopassi GA, Ramsey JJ, Lopez-Dominguez JA. A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice. Cell Metab. 2017 Sep 5;26(3):539-546.e5. doi:10.1016/j.cmet.2017.08.005. Erratum in: Cell Metab. 2018 May 1;27(5):1156. PMID:28877457.

Park SJ, Gavrilova O, Brown AL, Soto JE, Bremner S, Kim J, Xu X, Yang S, Um JH, Koch LG, Britton SL, Lieber RL, Philp A, Baar K, Kohama SG, Abel ED, Kim MK, Chung JH. DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging. Cell Metab. 2017 May 2;25(5):1135-1146.e7. doi:10.1016/j.cmet.2017.04.008. Erratum in: Cell Metab. 2017 Aug 1;26(2):447. PMID:28467930.

Shaw G, Lee-Barthel A, Ross ML, Wang B, Baar K. Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis. Am J Clin Nutr. 2017 Jan;105(1):136-143. doi:10.3945/ajcn.116.138594. Epub 2016 Nov 16. PMID:27852613.

Timmons JA, Baar K, Davidsen PK, Atherton PJ. Is irisin a human exercise gene? Nature. 2012 Aug 30;488(7413):E9-10; discussion E10-1. doi:10.1038/nature11364. PMID:22932392.

Park SJ, Ahmad F, Philp A, Baar K, Williams T, Luo H, Ke H, Rehmann H, Taussig R, Brown AL, Kim MK, Beaven MA, Burgin AB, Manganiello V, Chung JH. Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell. 2012 Feb 3;148(3):421-33. doi:10.1016/j.cell.2012.01.017. PMID:22304913.

Philp A, Chen A, Lan D, Meyer GA, Murphy AN, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K, Schenk S. Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise. J Biol Chem. 2011 Sep 2;286(35):30561-30570. doi:10.1074/jbc.M111.261685. Epub 2011 Jul 11. PMID:21757760.

Baar K, Wende AR, Jones TE, Marison M, Nolte LA, Chen M, Kelly DP, Holloszy JO. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. 2002 Dec;16(14):1879-86. doi:10.1096/fj.02-0367com. PMID:12468452.

Baar K, Esser K. Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise. Am J Physiol. 1999 Jan;276(1):C120-7. doi:10.1152/ajpcell.1999.276.1.C120. PMID:9886927.