IDDRC Publications | UC Davis MIND Institute

2024

Andrew PM, MacMahon JA, Bernardino PN, Tsai YH, Hobson BA, Porter VA, Huddleston SL, Luo AS, Bruun DA, Saito NH, Harvey DJ, Brooks-Kayal A, Chaudhari AJ, Lein PJ. Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate.  J Neuroinflammation. 2024 Nov 4;21(1):285. doi: 10.1186/s12974-024-03272-8.

Choi JW, Oh J, Bennett DH, Calafat AM, Schmidt RJ, Shin HM. Prenatal exposure to per- and polyfluoroalkyl substances and child behavioral problems.  Environ Res. 2024 Jun 15;251(Pt 1):118511. doi: 10.1016/j.envres.2024.118511.

Choi JW, Bennett DH, Calafat AM, Tancredi DJ, Miller M, Schmidt RJ, Shin HM. Gestational phthalate exposure and behavioral problems in preschool-aged children with increased likelihood of autism spectrum disorder.  Int J Hyg Environ Health. 2024 Nov 4;263:114483. doi: 10.1016/j.ijheh.2024.114483.

Dakopolos A, Condy E, Smith E, Harvey D, Kaat AJ, Coleman J, Riley K, Berry-Kravis E, Hessl D.  Developmental associations between cognition and adaptive behavior in intellectual and developmental disability.  J Neurodev Disord. 2024 Jun 13;16(1):31. doi: 10.1186/s11689-024-09542-z.

Dufour BD, Bartley T, McBride E, Allen E, McLennan YA, Hagerman RJ, Martínez-Cerdeño V. FXTAS Neuropathology Includes Widespread Reactive Astrogliosis and White Matter Specific Astrocyte Degeneration. Ann Neurol. 2024 Mar;95(3):558-575. doi: 10.1002/ana.26851.

Dwyer P, Sillas A, Prieto M, Camp E, Nordahl CW, Rivera SM. Hyper-focus, sticky attention, and springy attention in young autistic children: Associations with sensory behaviors and cognitive ability. Autism Res. 2024 Jun 5. doi: 10.1002/aur.3174.

Elahi H, Iosif AM, Mukherjee P, Hinshaw SP, Schweitzer JB. Using Hot and Cool Measures to Phenotype and Predict Functional Outcomes Across Dimensions of ADHD and Typical Development in Adolescents. Res Child Adolesc Psychopathol. 2024 Apr;52(4):579-593. doi: 10.1007/s10802-023-01149-7.

Fenton TA, Haouchine OY, Hallam EB, Smith EM, Jackson KC, Rahbarian D, Canales CP, Adhikari A, Nord AS, Ben-Shalom R, Silverman JL. Hyperexcitability and translational phenotypes in a preclinical mouse model of SYNGAP1-related intellectual disability. Transl Psychiatry. 2024 Oct 2;14(1):405. doi: 10.1038/s41398-024-03077-6.

Friedman L, Moser C, Thurman AJ, Taylor JL, Abbeduto L, Klusek J. Description and predictors of self-determination in males and females with fragile X syndrome on the verge of adulthood. J Intellect Disabil Res. 2024 Aug 12. doi: 10.1111/jir.13182.

French CD, Arnold CD, Taha AY, Engle-Stone R, Schmidt RJ, Hertz-Picciotto I, Slupsky CM. Assessing Repeated Urinary Proline Betaine Measures as a Biomarker of Usual Citrus Intake during Pregnancy: Sources of Within-Person Variation and Correlation with Reported Intake. Metabolites. 2023 Aug 2;13(8):904. doi: 10.3390/metabo13080904.

Ge R, Ching CRK, Bassett AS, Kushan L, Antshel KM, van Amelsvoort T, Bakker G, Butcher NJ, Campbell LE, Chow EWC, Craig M, Crossley NA, Cunningham A, Daly E, Doherty JL, Durdle CA, Emanuel BS, Fiksinski A, Forsyth JK, Fremont W, Goodrich-Hunsaker NJ, Gudbrandsen M, Gur RE, Jalbrzikowski M, Kates WR, Lin A, Linden DEJ, McCabe KL, McDonald-McGinn D, Moss H, Murphy DG, Murphy KC, Owen MJ, Villalon-Reina JE, Repetto GM, Roalf DR, Ruparel K, Schmitt JE, Schuite-Koops S, Angkustsiri K, Sun D, Vajdi A, van den Bree M, Vorstman J, Thompson PM, Vila-Rodriguez F, Bearden CE. Source-based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome. Hum Brain Mapp. 2024 Jan;45(1):e26553. doi: 10.1002/hbm.26553.

Hu H, Quon G. scPair: Boosting single cell multimodal analysis by leveraging implicit feature selection and single cell atlases. Nat Commun. 2024 Nov 15;15(1):9932. doi: 10.1038/s41467-024-53971-2.

Kadlaskar G, Iosif AM, Hatch B, de la Paz L, Chuang A, Soller MM, Morales-Martinez J, Tena KG, Sandler JP, Ozonoff S, Miller M. Delay of Gratification in Preschoolers with Autism and Concerns for ADHD. J Clin Child Adolesc Psychol. 2024 Oct 1:1-13. doi: 10.1080/15374416.2024.2405813.

Kim H, Le B, Goshi N, Zhu K, Grodzki AC, Lein PJ, Zhao M, Seker E. Primary cortical cell tri-culture to study effects of amyloid-β on microglia function and neuroinflammatory response. J Alzheimers Dis. 2024 Nov 5:13872877241291142. doi: 10.1177/13872877241291142.

Krug MK, Takarae Y, Iosif AM, Solomon M. Decision-making under conditions of explicit risk and uncertainty in autistic and typically developing adolescents and young adults. Cereb Cortex. 2024 May 2;34(13):1-7. doi: 10.1093/cercor/bhae097.

Mbachu CNP, Mbachu II, Hagerman R. A Comprehensive Review of Fragile X Syndrome and Fragile X Premutation Associated Conditions in Africa. Genes (Basel). 2024 May 25;15(6):683. doi: 10.3390/genes15060683.

McKinney WS, Williford DN, Abbeduto L, Schmitt LM. The impact of social-environmental factors on IQ in syndromic intellectual developmental disabilities. J Clin Transl Sci. 2024 Apr 5;8(1):e59. doi: 10.1017/cts.2024.510.

Moser C, Campanelli A, Friedman L, Thurman AJ, Roberts JE, Abbeduto L, Klusek J. Characterizing the social interaction style of autism in young adult males with fragile X syndrome. J Intellect Disabil Res. 2024 Jan 23. doi: 10.1111/jir.13121.

Ozonoff S, Young GS, Bradshaw J, Charman T, Chawarska K, Iverson JM, Klaiman C, Landa RJ, McDonald N, Messinger D, Schmidt RJ, Wilkinson CL, Zwaigenbaum L. Familial Recurrence of Autism: Updates From the Baby Siblings Research Consortium. Pediatrics. 2024 Jul 16:e2023065297. doi: 10.1542/peds.2023-065297.

Potter SN, Harvey D, Sterling A, Abbeduto L. Parental Responsivity and Child Communication During Mother-Child and Father-Child Interactions in Fragile X Syndrome. J Speech Lang Hear Res. 2024 Feb 26:1-21. doi: 10.1044/2023_JSLHR-23-00517.

Protic D, Breeze E, Mendoza G, Zafarullah M, Abbeduto L, Hagerman R, Coffey C, Cudkowicz M, Durbin-Johnson B, Ashwood P, Berry-Kravis E, Erickson CA, Filipink R, Gropman A, Lehwald L, Maxwell-Horn A, Morris S, Bennett AP, Prock L, Talboy A, Tartaglia N, Veenstra-VanderWeele J, Tassone F. Negative effect of treatment with mGluR5 negative allosteric modulator AFQ056 on blood biomarkers in young individuals with Fragile X syndrome. SAGE Open Med. 2024 Sep 29;12:20503121241282401. doi: 10.1177/20503121241282401.

Punatar R, Angkustsiri K, Kair LR, Tancredi DJ, Harvey DJ, Schmidt RJ. Association of Breastfeeding Duration with Neurodevelopmental Outcomes in an Enriched Familial Likelihood Cohort for Autism Spectrum Disorder. Child Psychiatry Hum Dev. 2024 Apr 24. doi: 10.1007/s10578-024-01700-7.

Randol JL, Kim K, Ponzini MD, Tassone F, Falcon AK, Hagerman RJ, Hagerman PJ. Variation of FMRP Expression in Peripheral Blood Mononuclear Cells from Individuals with Fragile X Syndrome. Genes (Basel). 2024 Mar 13;15(3):356. doi: 10.3390/genes15030356.

Schmidt D, Urias C, Dufek S, Talbott MR. Caregiver Perspectives on Telehealth Assessment and Other Supports for Infants with Early Developmental Concerns. J Autism Dev Disord. 2024 Jul 27. doi: 10.1007/s10803-024-06483-3

Seng P, Montanaro FAM, Biag HMB, Salcedo-Arellano MJ, Kim K, Ponzini MD, Tassone F, Schneider A, Abbeduto L, Thurman AJ, Hessl D, Bolduc FV, Jacquemont S, Lippé S, Hagerman RJ. Longitudinal follow-up of metformin treatment in Fragile X Syndrome. Front Psychol. 2024 Jun 13;15:1305597. doi: 10.3389/fpsyg.2024.1305597.

Sharifi O, Haghani V, Neier KE, Fraga KJ, Korf I, Hakam SM, Quon G, Johansen N, Yasui DH, LaSalle JM. Sex-specific single cell-level transcriptomic signatures of Rett syndrome disease progression. Commun Biol. 2024 Oct 10;7(1):1292. doi: 10.1038/s42003-024-06990-0.

Stahmer AC, Dufek S, Rogers SJ, Iosif AM. Study Protocol for a Cluster, Randomized, Controlled Community Effectiveness Trial of the Early Start Denver Model (ESDM) Compared to Community Early Behavioral Intervention (EBI) in Community Programs serving Young Autistic Children: Partnering for Autism: Learning more to improve Services (PALMS). BMC Psychol. 2024 Sep 28;12(1):513. doi: 10.1186/s40359-024-02020-0.

Tak Y, Tassone F, Hagerman RJ. Case Series: Vestibular Migraines in Fragile X Premutation Carriers. J Clin Med. 2024 Jan 16;13(2):504. doi: 10.3390/jcm13020504.

Tak Y, Schneider A, Santos E, Randol JL, Tassone F, Hagerman P, Hagerman RJ. Unmethylated Mosaic Full Mutation Males without Fragile X Syndrome. Genes (Basel). 2024 Mar 3;15(3):331. doi: 10.3390/genes15030331.

Talbott MR, Young GS, Ozonoff S. Can combining existing behavioral tools improve identification of infants at elevated likelihood of autism in the first year of life?  Autism. 2024 Sep 12:13623613241275455. doi: 10.1177/13623613241275455.

Thurman AJ, Nunnally AD, Nguyen V, Berry-Kravis E, Sterling A, Edgin J, Hamilton D, Aschkenasy J, Abbeduto L. Short-term and Long-term Stability of the Autism Diagnostic Observation Schedule (ADOS-2) Calibrated Comparison Scores (CCS) and Classification Scores in Youth with Down Syndrome or Fragile X Syndrome with Intellectual Disability. J Autism Dev Disord. 2024 Sep 9. doi: 10.1007/s10803-024-06535-8.

Tsai YH, González EA, Grodzki ACG, Bruun DA, Saito NH, Harvey DJ, Lein PJ. Acute intoxication with diisopropylfluorophosphate promotes cellular senescence in the adult male rat brain. Front Toxicol. 2024 Apr 30;6:1360359. doi: 10.3389/ftox.2024.1360359.

Van Deusen K, Prince MA, Walsh MM, Esbensen AJ, Patel LR, Pinks ME, Thurman AJ, Abbeduto L, Daunhauer LA, Fidler DJ. Laboratory-based measures of executive function and daily living skills in young children with Down syndrome: informing future interventions. J Intellect Disabil Res. 2024 Aug 7. doi: 10.1111/jir.13176.

Wilson RB, Vangala S, Reetzke R, Pierges A, Ozonoff S, Miller M. Objective measurement of movement variability using wearable sensors predicts ASD outcomes in infants at high likelihood for ASD and ADHD. Autism Res. 2024 May 15. doi: 10.1002/aur.3150.

Wilson RJ, Suh YP, Dursun I, Li X, da Costa Souza F, Grodzki AC, Cui JY, Lehmler HJ, Lein PJ. Developmental exposure to the Fox River PCB mixture modulates behavior in juvenile mice. Neurotoxicology. 2024 Jul;103:146-161. doi: 10.1016/j.neuro.2024.06.008.

Winarni TI, Hwang YH, Rivera SM, Hessl D, Durbin-Johnson BP, Utari A, Hagerman R, Tassone F. Apolipoproteine and KLOTHO Gene Variants Do Not Affect the Penetrance of Fragile X-Associated Tremor/Ataxia Syndrome.  Int J Mol Sci. 2024 Jul 25;25(15):8103. doi: 10.3390/ijms25158103.

2023

Abbeduto L, Del Hoyo Soriano L, Berry-Kravis E, Sterling A, Edgin JO, Abdelnur N, Drayton A, Hoffmann A, Hamilton D, Harvey DJ, Thurman AJ. Expressive language sampling and outcome measures for treatment trials in fragile X and down syndromes: composite scores and psychometric properties. Sci Rep. 2023 Jun 7;13(1):9267. doi: 10.1038/s41598-023-36087-3.

Akintunde ME, Lin YP, Krakowiak P, Pessah IN, Hertz-Picciotto I, Puschner B, Ashwood P, Van de Water J. Ex vivo exposure to polybrominated diphenyl ether (PBDE) selectively affects the immune response in autistic children. Brain Behav Immun Health. 2023 Oct 28;34:100697. doi: 10.1016/j.bbih.2023.100697.

Aishworiya R, Biag HMB, Salcedo-Arellano MJ, Musa Z, Schneider A, Clark C, Santos E, Tassone F, Hagerman R. Fragile X Syndrome and Fetal Alcohol Syndrome: Occurrence of Dual Diagnosis in a Set of Triplets. J Dev Behav Pediatr. 2023 Aug 8. doi: 10.1097/DBP.0000000000001204.

Aishworiya R, Chi MH, Zafarullah M, Mendoza G, Ponzini MD, Kim K, Biag HMB, Thurman AJ, Abbeduto L, Hessl D, Randol JL, Bolduc FV, Jacquemont S, Lippé S, Hagerman P, Hagerman R, Schneider A, Tassone F. Intercorrelation of Molecular Biomarkers and Clinical Phenotype Measures in Fragile X Syndrome. Cells. 2023 Jul 24;12(14):1920. doi: 10.3390/cells12141920.

Aishworiya R, Hwang YH, Santos E, Hayward B, Usdin K, Durbin-Johnson B, Hagerman R, Tassone F. Clinical implications of somatic allele expansion in female FMR1 premutation carriers. Sci Rep. 2023 Apr 29;13(1):7050. doi: 10.1038/s41598-023-33528-x.

Aishworiya R, Tak YE, Ponzini MD, Biag HMB, Salcedo-Arellano MJ, Kim K, Tassone F, Schneider A, Thurman AJ, Abbeduto L, Hessl D, Randol JL, Bolduc FV, Lippe S, Hagerman P, Hagerman R. Adaptive, behavioral, and cognitive outcomes in individuals with fragile X syndrome with varying autism severity. Int J Dev Neurosci. 2023 Sep 19. doi: 10.1002/jdn.10299.

Beitnere U, Vilanova-Cuevas B, Christian SG, Taylor C, Berg EL, Copping NA, Dindot SV, Silverman JL, Gareau MG, Segal DJ. Unique Features of the Gut Microbiome Characterized in Animal Models of Angelman Syndrome. mSystems. 2023 Jan 4:e0060822. doi: 10.1128/msystems.00608-22.

Bruce MR, Couch ACM, Grant S, McLellan J, Ku K, Chang C, Bachman A, Matson M, Berman RF, Maddock RJ, Rowland D, Kim E, Ponzini MD, Harvey D, Taylor SL, Vernon AC, Bauman MD, Van de Water J. Altered behavior, brain structure, and neurometabolites in a rat model of autism-specific maternal autoantibody exposure. Mol Psychiatry. 2023 Mar 27. doi: 10.1038/s41380-023-02020-3.

Choi Y, Li R, Quon G. siVAE: interpretable deep generative models for single-cell transcriptomes. Genome Biol. 2023 Feb 20;24(1):29. doi: 10.1186/s13059-023-02850-y.

Costa AN, Ferguson BJ, Hawkins E, Coman A, Schauer J, Ramirez-Celis A, Hecht PM, Bruce D, Tilley M, Talebizadeh Z, Van de Water J, Beversdorf DQ. The Relationship between Maternal Antibodies to Fetal Brain and Prenatal Stress Exposure in Autism Spectrum Disorder. Metabolites. 2023 May 16;13(5):663. doi: 10.3390/metabo13050663.

da Costa Souza F, Grodzki ACG, Morgan RK, Zhang Z, Taha AY, Lein PJ. Oxidized linoleic acid metabolites regulate neuronal morphogenesis in vitro. Neurochem Int. 2023 Mar;164:105506. doi: 10.1016/j.neuint.2023.105506.

Crawley JN. Twenty Years of Discoveries Emerging from Mouse Models of Autism. Neurosci Biobehav Rev. 2023 Jan 19:105053. doi: 10.1016/j.neubiorev.2023.105053.

Croen LA, Ames JL, Qian Y, Alexeeff S, Ashwood P, Gunderson EP, Wu YW, Boghossian AS, Yolken R, Van de Water J, Weiss LA. Inflammatory Conditions During Pregnancy and Risk of Autism and Other Neurodevelopmental Disorders. Biol Psychiatry Glob Open Sci. 2023 Oct 11;4(1):39-50. doi: 10.1016/j.bpsgos.2023.09.008.

Dimachkie Nunnally A, Factor RS, Sturm A, Valluripalli Soorya L, Wainer A, Taylor S, Ponzini M, Abbeduto L, Gulsrud AC. Examining indicators of psychosocial risk and resilience in parents of autistic children. Front Behav Neurosci. 2023 May 15;17:1102516. doi: 10.3389/fnbeh.2023.1102516.

Duis J, Skinner A, Carson R, Gouelle A, Annoussamy M, Silverman JL, Apkon S, Servais L, Carollo J. Quantitative measures of motor development in Angelman syndrome. Am J Med Genet A. 2023 Apr 5. doi: 10.1002/ajmg.a.63192.

Eldeeb SY, Ludwig NN, Wieckowski AT, Dieckhaus MF, Algur Y, Ryan V, Dufek S, Stahmer A, Robins DL. Sex differences in early autism screening using the Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT-R/F). Autism. 2023 Feb 14:13623613231154728. doi: 10.1177/13623613231154728.

French CD, Arnold CD, Taha AY, Engle-Stone R, Schmidt RJ, Hertz-Picciotto I, Slupsky CM. Assessing Repeated Urinary Proline Betaine Measures as a Biomarker of Usual Citrus Intake during Pregnancy: Sources of Within-Person Variation and Correlation with Reported Intake. Metabolites. 2023 Aug 2;13(8):904. doi: 10.3390/metabo13080904.

Goshi N, Kim H, Girardi G, Gardner A, Seker E. Electrophysiological Activity of Primary Cortical Neuron-Glia Mixed Cultures. Cells. 2023 Mar 6;12(5):821. doi: 10.3390/cells12050821.

Hessl D, Mandujano Rojas K, Ferrer E, Espinal G, Famula J, Schneider A, Hagerman R, Tassone F, Rivera SM. FMR1 Carriers Report Executive Function Changes Prior to Fragile X-Associated Tremor/Ataxia Syndrome: A Longitudinal Study. Mov Disord. 2023 Dec 20. doi: 10.1002/mds.29695.

Hong T, McBride E, Dufour BD, Falcone C, Doan M, Noctor SG, Martínez-Cerdeño V. Synaptic boutons are smaller in chandelier cell cartridges in autism.  PLoS One. 2023 Apr 25;18(4):e0281477. doi: 10.1371/journal.pone.0281477

Islam A, Ronco A, Becker SM, Blackburn J, Schittny JC, Kim K, Stein-Wexler R, Wexler AS. Can lung airway geometry be used to predict autism? A preliminary machine learning-based study. Anat Rec (Hoboken). 2023 Sep 28. doi: 10.1002/ar.25332.

Johansen N, Hu H, Quon G. Projecting RNA measurements onto single cell atlases to extract cell type-specific expression profiles using scProjection. Nat Commun. 2023 Aug 25;14(1):5192. doi: 10.1038/s41467-023-40744-6.

Karunungan K, Garza RH, Grodzki AC, Holt M, Lein PJ, Chandrasekaran V. Gamma secretase activity modulates BMP-7-induced dendritic growth in primary rat sympathetic neurons. Auton Neurosci. 2023 Jul;247:103085. doi: 10.1016/j.autneu.2023.103085.

Keil-Stietz K, Lein PJ. Gene×environment interactions in autism spectrum disorders. Curr Top Dev Biol. 2023;152:221-284. doi: 10.1016/bs.ctdb.2022.11.001.

Klusek J, Will E, Moser C, Hills K, Thurman AJ, Abbeduto L, Roberts JE. Predictors, Parental Views, and Concordance Across Diagnostic Sources of Autism in Male Youth with Fragile X Syndrome: Clinical Best Estimate and Community Diagnoses. Res Child Adolesc Psychopathol. 2023 Mar 3. doi: 10.1007/s10802-023-01044-1.

LaSalle JM. Epigenomic signatures reveal mechanistic clues and predictive markers for autism spectrum disorder. Mol Psychiatry. 2023 Jan 17. doi: 10.1038/s41380-022-01917-9.

Lesh TA, Iosif AM, Tanase C, Vlasova RM, Ryan AM, Bennett J, Hogrefe CE, Maddock RJ, Geschwind DH, Van de Water J, McAllister AK, Styner MA, Bauman MD, Carter CS. Extracellular free water elevations are associated with brain volume and maternal cytokine response in a longitudinal nonhuman primate maternal immune activation model. Mol Psychiatry. 2023 Aug 15. doi: 10.1038/s41380-023-02213-w.

MacFarlane H, Salem AC, Bedrick S, Dolata JK, Wiedrick J, Lawley GO, Finestack LH, Kover ST, Thurman AJ, Abbeduto L, Fombonne E. Consistency and reliability of automated language measures across expressive language samples in autism. Autism Res. 2023 Feb 1. doi: 10.1002/aur.2897.

McCanlies EC, Gu JK, Kashon M, Yucesoy B, Ma CC, Sanderson WT, Kim K, Ludeña-Rodriguez YJ, Hertz-Picciotto I. Parental occupational exposure to solvents and autism spectrum disorder: An exploratory look at gene-environment interactions. Environ Res. 2023 Mar 31;228:115769. doi: 10.1016/j.envres.2023.115769.

Mouat JS, Li X, Neier K, Zhu Y, Mordaunt CE, La Merrill MA, Lehmler HJ, Jones MP, Lein PJ, Schmidt RJ, LaSalle JM. Networks of placental DNA methylation correlate with maternal serum PCB concentrations and child neurodevelopment. Environ Res. 2023 Mar 1;220:115227. doi: 10.1016/j.envres.2023.115227.

Ozonoff S, Hill MM, Hill A, Ashley K, Young GS. Factors related to retention in a longitudinal study of infants at familial risk for autism. JCPP Adv. 2023 Jan 26;3(1):e12140. doi: 10.1002/jcv2.12140.

Parikh C, Ozonoff S. Brief Report: Single and Repeat Screening with the Modified Checklist for Autism in Toddlers-Revised in Young Children at Higher Likelihood for Autism Spectrum Disorder. J Autism Dev Disord. 2023 Oct 31. doi: 10.1007/s10803-023-06138-9.

Peng M, Lovos A, Bottrill K, Hughes K, Sampsel M, Lee NR, Abbeduto L, Thurman AJ, Edgin J. Extended trajectory of spatial memory errors in typical and atypical development: The role of binding and precision. Hippocampus. 2023 Sep 14. doi: 10.1002/hipo.23576.

Pinks ME, Van Deusen K, Prince MA, Esbensen AJ, Thurman AJ, Patel LR, Abbeduto L, Walsh MM, Daunhauer LA, Feigles RT, Nguyen V, Fidler DJ. Psychometric evaluation of a working memory assessment measure in young children with Down syndrome. Res Dev Disabil. 2023 Jul 12;139:104564. doi: 10.1016/j.ridd.2023.104564.

Protic D, Polli R, Hwang YH, Mendoza G, Hagerman R, Durbin-Johnson B, Hayward BE, Usdin K, Murgia A, Tassone F. Activation Ratio Correlates with IQ in Female Carriers of the FMR1 Premutation. Cells. 2023 Jun 24;12(13):1711. doi: 10.3390/cells12131711.

Salcedo-Arellano MJ, Johnson MD, McLennan YA, Hwang YH, Juarez P, McBride EL, Pantoja AP, Durbin-Johnson B, Tassone F, Hagerman RJ, Martínez-Cerdeño V. Brain Metabolomics in Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS). Cells. 2023 Aug 23;12(17):2132. doi: 10.3390/cells12172132.

Santos E, Clark C, Biag HMB, Tang SJ, Kim K, Ponzini MD, Schneider A, Giulivi C, Montanaro FAM, Gipe JT, Dayton J, Randol JL, Yao PJ, Manolopoulos A, Kapogiannis D, Hwang YH, Hagerman P, Hagerman R, Tassone F. Open-Label Sulforaphane Trial in FMR1 Premutation Carriers with Fragile-X-Associated Tremor and Ataxia Syndrome (FXTAS). Cells. 2023 Dec 5;12(24):2773. doi: 10.3390/cells12242773.

Shields RH, Kaat A, Sansone SM, Michalak C, Coleman J, Thompson T, McKenzie FJ, Dakopolos A, Riley K, Berry-Kravis E, Widaman KF, Gershon RC, Hessl D. Sensitivity of the NIH Toolbox to Detect Cognitive Change in Individuals With Intellectual and Developmental Disability. Neurology. 2023 Feb 21;100(8):e778-e789. doi: 10.1212/WNL.0000000000201528.

Silverman JL. Animal models for psychiatric research: Novel directions for behavioral neuroscience in translation. Neurosci Biobehav Rev. 2023 Sep;152:105309. doi: 10.1016/j.neubiorev.2023.105309.

Tat L, Cannizzaro N, Schaaf Z, Racherla S, Bottiglieri T, Green R, Zarbalis KS. Prenatal folic acid and vitamin B12 imbalance alter neuronal morphology and synaptic density in the mouse neocortex. Commun Biol. 2023 Nov 8;6(1):1133. doi: 10.1038/s42003-023-05492-9.

Talapatra D, Snider L, Coleman J, Thompson T, Reinhardt JS, Hessl D, Riley K. Deviation scores: An innovative approach to interpreting cognitive test results for individuals with intellectual disabilities. J Appl Res Intellect Disabil. 2023 Aug 8. doi: 10.1111/jar.13137.

Van Deusen K, Prince MA, Thurman AJ, Esbensen AJ, Patel LR, Abbeduto L, Walsh MM, Daunhauer LA, Feigles RT, Fidler DJ. Evaluating an adapted reverse categorisation task to assess cognitive flexibility in young children with Down syndrome. J Intellect Disabil Res. 2023 May 23. doi: 10.1111/jir.13040.

Vargas MV, Dunlap LE, Dong C, Carter SJ, Tombari RJ, Jami SA, Cameron LP, Patel SD, Hennessey JJ, Saeger HN, McCorvy JD, Gray JA, Tian L, Olson DE. Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. Science. 2023 Feb 17;379(6633):700-706. doi: 10.1126/science.adf0435.

Weiner MW, Veitch DP, Miller MJ, Aisen PS, Albala B, Beckett LA, Green RC, Harvey D, Jack CR Jr, Jagust W, Landau SM, Morris JC, Nosheny R, Okonkwo OC, Perrin RJ, Petersen RC, Rivera-Mindt M, Saykin AJ, Shaw LM, Toga AW, Tosun D, Trojanowski JQ; Alzheimer's Disease Neuroimaging Initiative. Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4. Alzheimers Dement. 2023 Jan;19(1):307-317. doi: 10.1002/alz.12797.

2022

Adhikari A, Buchanan FKB, Fenton TA, Cameron DL, Halmai JANM, Copping NA, Fink KD, Silverman JL. Touchscreen cognitive deficits, hyperexcitability and hyperactivity in males and females using two models of Cdkl5 deficiency. Hum Mol Genet. 2022 Sep 10;31(18):3032-3050. doi: 10.1093/hmg/ddac091.

Aishworiya R, Valica T, Hagerman R, Restrepo B. An Update on Psychopharmacological Treatment of Autism Spectrum Disorder. Neurotherapeutics. 2022 Jan;19(1):248-262. doi: 10.1007/s13311-022-01183-1.

Aishworiya R, Protic D, Hagerman R. Autism spectrum disorder in the fragile X premutation state: possible mechanisms and implications. J Neurol. 2022 Jun 20. doi: 10.1007/s00415-022-11209-5.

Aishworiya R, Protic D, Tang SJ, Schneider A, Tassone F, Hagerman R. Fragile X-Associated Neuropsychiatric Disorders (FXAND) in Young Fragile X Premutation Carriers. Genes (Basel). 2022 Dec 17;13(12):2399. doi: 10.3390/genes13122399.

Andrews DS, Aksman L, Kerns CM, Lee JK, Winder-Patel BM, Harvey DJ, Waizbard-Bartov E, Heath B, Solomon M, Rogers SJ, Altmann A, Nordahl CW, Amaral DG. Association of Amygdala Development With Different Forms of Anxiety in Autism Spectrum Disorder. Biol Psychiatry. 2022 Jun 1;91(11):977-987. doi: 10.1016/j.biopsych.2022.01.016.

Angkustsiri K, Fussell JJ, Bennett A, Schauer J, Ramirez-Celis A, Hansen RL, Van de Water J. Pilot Study of Maternal Autoantibody-Related Autism. J Dev Behav Pediatr. 2022 Oct-Nov 01;43(8):465-471. doi: 10.1097/DBP.0000000000001100.

Bangert K, Scott KS, Adams C, Kisenwether JS, Giuffre L, Reed J, Thurman AJ, Abbeduto L, Klusek J. Cluttering in the Speech of Young Men With Fragile X Syndrome. J Speech Lang Hear Res. 2022 Feb 23:1-16. doi: 10.1044/2021_JSLHR-21-00446.

Bauman MD, Buss C. Maternal Proinflammatory Processes and Fetal Neurodevelopment: Integrating Clinical and Preclinical Research Approaches and Identifying Knowledge Gaps That Warrant Future Collaboration. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 May;7(5):444-446. doi: 10.1016/j.bpsc.2022.03.009.

Bennett DH, Busgang SA, Kannan K, Parsons PJ, Takazawa M, Palmer CD, Schmidt RJ, Doucette JT, Schweitzer JB, Gennings C, Hertz-Picciotto I. Environmental exposures to pesticides, phthalates, phenols and trace elements are associated with neurodevelopment in the CHARGE study. Environ Int. 2022 Jan 24;161:107075. doi: 10.1016/j.envint.2021.107075.

Busgang SA, Waller LA, Colicino E, D'Agostino R Jr, Hertz-Picciotto I, Gennings C. Selecting External Controls for Internal Cases Using Stratification Score Matching Methods. Int J Environ Res Public Health. 2022 Feb 23;19(5):2549. doi: 10.3390/ijerph19052549.

Calub CA, Benyakorn S, Sun S, Iosif AM, Boyle LH, Solomon M, Hessl D, Schweitzer JB. Working Memory Training in Youth With Autism, Fragile X, and Intellectual Disability: A Pilot Study. Am J Intellect Dev Disabil. 2022 Sep 1;127(5):369-389. doi: 10.1352/1944-7558-127.5.369.

Channell MM, Sandstrom LE, Harvey D. Mental State Language Development in Children With Down Syndrome Versus Typical Development. Am J Intellect Dev Disabil. 2022 Nov 1;127(6):495-510. doi: 10.1352/1944-7558-127.6.495.

Chen H, Carty RK, Bautista AC, Hayakawa KA, Lein PJ. Triiodothyronine or Antioxidants Block the Inhibitory Effects of BDE-47 and BDE-49 on Axonal Growth in Rat Hippocampal Neuron-Glia Co-Cultures. Toxics. 2022 Feb 18;10(2):92. doi: 10.3390/toxics10020092

Davis K, Iosif AM, Nordahl CW, Solomon M, Krug MK. Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder. J Autism Dev Disord. 2022 Jul 12. doi: 10.1007/s10803-022-05649-1.

Del Hoyo Soriano L, Sterling A, Edgin J, Hamilton DR, Berry-Kravis E, Dimachkie Nunnally A, Thurman AJ, Abbeduto L. Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome. J Autism Dev Disord. 2022 Oct 31. doi: 10.1007/s10803-022-05779-6.

Del Hoyo Soriano L, Villarreal JC, Sterling A, Edgin J, Berry-Kravis E, Hamilton DR, Thurman AJ, Abbeduto L. The association between expressive language skills and adaptive behavior in individuals with Down syndrome. Sci Rep. 2022 Nov 21;12(1):20014. doi: 10.1038/s41598-022-24478-x.

Esbensen AJ, Schworer EK, Fidler DJ, Thurman AJ. Considerations for measuring individual outcomes across contexts in Down syndrome: Implications for research and clinical trials. Int Rev Res Dev Disabil. 2022;62:191-225. doi: 10.1016/bs.irrdd.2022.05.005.

Famula J, Ferrer E, Hagerman RJ, Tassone F, Schneider A, Rivera SM, Hessl D. Neuropsychological changes in FMR1 premutation carriers and onset of fragile X-associated tremor/ataxia syndrome. J Neurodev Disord. 2022 Mar 23;14(1):23. doi: 10.1186/s11689-022-09436-y.

Fidler DJ, Prince MA, Van Deusen K, Esbensen AJ, Thurman AJ, Abbeduto L, Patel L, Mervis C, Schworer EK, Lee NR, Edgin JO, Hepburn S, Davis S, Daunhauer LA.  Latent profiles of autism symptoms in children and adolescents with Down syndrome. J Intellect Disabil Res. 2022 Jan 4. doi: 10.1111/jir.12910.

Granillo L, Iosif AM, Goodrich A, Snyder NW, Schmidt RJ. Maternal androgens and autism spectrum disorder in the MARBLES prospective cohort study. Res Autism Spectr Disord. 2022 Nov;99:102054. doi: 10.1016/j.rasd.2022.102054.

Giulivi C, Wang JY, Hagerman RJ. Artificial neural network applied to fragile X-associated tremor/ataxia syndrome stage diagnosis based on peripheral mitochondrial bioenergetics and brain imaging outcomes. Sci Rep. 2022 Dec 10;12(1):21382. doi: 10.1038/s41598-022-25615-2.

Goshi N, Girardi G, da Costa Souza F, Gardner A, Lein PJ, Seker E. Influence of microchannel geometry on device performance and electrophysiological recording fidelity during long-term studies of connected neural populations. Lab Chip. 2022 Sep 16. doi: 10.1039/d2lc00683a.

Goshi N, Kim H, Seker E. Primary Cortical Cell Tri-Culture-Based Screening of Neuroinflammatory Response in Toll-like Receptor Activation. Biomedicines. 2022 Aug 29;10(9):2122. doi: 10.3390/biomedicines10092122.

Hanson KL, Grant SE, Funk LH, Schumann CM, Bauman MD. Impact of Maternal Immune Activation on Nonhuman Primate Prefrontal Cortex Development: Insights for Schizophrenia. Biol Psychiatry. 2022 Sep 15;92(6):460-469. doi: 10.1016/j.biopsych.2022.04.004.

Hasegawa Y, Zhang Z, Taha AY, Capitanio JP, Bauman MD, Golub MS, Van de Water J, VandeVoort CA, Walker CK, Slupsky CM. Impact of Maternal Obesity on the Gestational Metabolome and Infant Metabolome, Brain, and Behavioral Development in Rhesus Macaques. Metabolites. 2022 Aug 19;12(8):764. doi: 10.3390/metabo12080764.

Hoffmann A, Thurman AJ, Sterling A, Kover ST, Finestack L, Berry-Kravis E, Edgin JO, Drayton A, Fombonne E, Abbeduto L. Analysis of a Repetitive Language Coding System: Comparisons between Fragile X Syndrome, Autism, and Down Syndrome. Brain Sci. 2022 Apr 29;12(5):575. doi: 10.3390/brainsci12050575.

Jasoliya M, Gu J, AlOlaby RR, Durbin-Johnson B, Chedin F, Tassone F. Profiling Genome-Wide DNA Methylation in Children with Autism Spectrum Disorder and in Children with Fragile X Syndrome. Genes (Basel). 2022 Oct 4;13(10):1795. doi: 10.3390/genes13101795.

John Thurman A, Hoyos Alvarez C, Nguyen V. Using weighted communication scoring procedures in naturalistic play samples: Preliminary validation in preschool-aged boys with autism or fragile X syndrome. Autism Res. 2022 Apr 7. doi: 10.1002/aur.2724.

Johnson D, Santos E, Kim K, Ponzini MD, McLennan YA, Schneider A, Tassone F, Hagerman RJ. Increased Pain Symptomatology Among Females vs. Males With Fragile X-Associated Tremor/Ataxia Syndrome. Front Psychiatry. 2022 Jan 20;12:762915. doi: 10.3389/fpsyt.2021.762915.

Klusek J, Fairchild A, Moser C, Mailick MR, Thurman AJ, Abbeduto L. Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation. J Neurodev Disord. 2022 Jan 14;14(1):7. doi: 10.1186/s11689-022-09415-3.

Klusek J, O'Connor SL, Hickey A, Hills KJ, Abbeduto L, Roberts JE. Attention/Deficit Hyperactivity Disorder in Adolescent and Young Adult Males With Fragile X Syndrome. Am J Intellect Dev Disabil. 2022 May 1;127(3):213-230. doi: 10.1352/1944-7558-127.3.213.

Laufer BI, Neier K, Valenzuela AE, Yasui DH, Schmidt RJ, Lein PJ, LaSalle JM. Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure. Cell Rep. 2022 Mar 1;38(9):110442. doi: 10.1016/j.celrep.2022.110442.

Lee JK, Andrews DS, Ozturk A, Solomon M, Rogers S, Amaral DG, Nordahl CW. Altered Development of Amygdala-Connected Brain Regions in Males and Females with Autism. J Neurosci. 2022 Jun 27:JN-RM-0053-22. doi: 10.1523/JNEUROSCI.0053-22.2022.

Lee JK, Cho ACB, Andrews DS, Ozonoff S, Rogers SJ, Amaral DG, Solomon M, Nordahl CW. Default mode and fronto-parietal network associations with IQ development across childhood in autism. J Neurodev Disord. 2022 Sep 15;14(1):51. doi: 10.1186/s11689-022-09460-y.

Liang N, Emami S, Patten KT, Valenzuela AE, Wallis CD, Wexler AS, Bein KJ, Lein PJ, Taha AY. Chronic exposure to traffic-related air pollution reduces lipid mediators of linoleic acid and soluble epoxide hydrolase in serum of female rats. Environ Toxicol Pharmacol. 2022 Jul;93:103875. doi: 10.1016/j.etap.2022.103875.

McLennan YA, Mosconi MW, McKenzie FJ, Famula J, Krawchuk B, Kim K, Clark CJ, Hessl D, Rivera SM, Simon TJ, Tassone F, Hagerman RJ. Prosaccade and Antisaccade Behavior in Fragile X-Associated Tremor/Ataxia Syndrome Progression. Mov Disord Clin Pract. 2022 Apr 28;9(4):473-478. doi: 10.1002/mdc3.13449.

Mordaunt CE, Mouat JS, Schmidt RJ, LaSalle JM. Comethyl: a network-based methylome approach to investigate the multivariate nature of health and disease. Brief Bioinform. 2022 Jan 17:bbab554. doi: 10.1093/bib/bbab554.

Mukherjee P, Vilgis V, Rhoads S, Chahal R, Fassbender C, Leibenluft E, Dixon JF, Pakyurek M, van den Bos W, Hinshaw SP, Guyer AE, Schweitzer JB. Associations of Irritability With Functional Connectivity of Amygdala and Nucleus Accumbens in Adolescents and Young Adults With ADHD. J Atten Disord. 2022 May;26(7):1040-1050. doi: 10.1177/10870547211057074.

Parenti M, Schmidt RJ, Ozonoff S, Shin HM, Tancredi DJ, Krakowiak P, Hertz-Picciotto I, Walker CK, Slupsky CM. Maternal Serum and Placental Metabolomes in Association with Prenatal Phthalate Exposure and Neurodevelopmental Outcomes in the MARBLES Cohort. Metabolites. 2022 Sep 2;12(9):829. doi: 10.3390/metabo12090829.

Patten KT, Valenzuela AE, Wallis C, Harvey DJ, Bein KJ, Wexler AS, Gorin FA, Lein PJ.  Hippocampal but Not Serum Cytokine Levels Are Altered by Traffic-Related Air Pollution in TgF344-AD and Wildtype Fischer 344 Rats in a Sex- and Age-Dependent Manner. Front Cell Neurosci. 2022 Apr 22;16:861733. doi: 10.3389/fncel.2022.861733.

Petkova SP, Adhikari A, Berg EL, Fenton TA, Duis J, Silverman JL. Gait as a quantitative translational outcome measure in Angelman syndrome. Autism Res. 2022 Mar 10. doi: 10.1002/aur.2697.

Potter SN, Bullard L, Banasik A, Feigles RT, Nguyen V, McDuffie A, Thurman AJ, Hagerman R, Abbeduto L. Family and Caregiver Characteristics Contribute to Caregiver Change in Use of Strategies and Growth in Child Spoken Language in a Parent-Implemented Language Intervention in Fragile X Syndrome. Perspect ASHA Spec Interest Groups. 2022 Dec;7(6):1630-1644. doi: 10.1044/2022_persp-22-00016.

Potter SN, Harvey DJ, Sterling A, Abbeduto L. Mental Health Challenges, Parenting Stress, and Features of the Couple Relationship in Parents of Children With Fragile X Syndrome. Front Psychiatry. 2022 Apr 1;13:857633. doi: 10.3389/fpsyt.2022.857633.

Ramirez-Celis A, Croen LA, Yoshida CK, Alexeeff SE, Schauer J, Yolken RH, Ashwood P, Van de Water J. Maternal autoantibody profiles as biomarkers for ASD and ASD with co-occurring intellectual disability. Mol Psychiatry. 2022 May 26. doi: 10.1038/s41380-022-01633-4.

Ryan AM, Bauman MD. Primate models as a translational tool for understanding prenatal origins of neurodevelopmental disorders associated with maternal infection. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Mar 8:S2451-9022(22)00051-9. doi: 10.1016/j.bpsc.2022.02.012

Salcedo-Arellano MJ, Hagerman RJ. Recent research in fragile X-associated tremor/ataxia syndrome. Curr Opin Neurobiol. 2022 Feb;72:155-159. doi: 10.1016/j.conb.2021.11.006.

Schworer EK, Esbensen AJ, Nguyen V, Bullard L, Fidler DJ, Daunhauer LA, Mervis CB, Becerra AM, Abbeduto L, Thurman AJ. Patterns and predictors of adaptive skills in 2- to 7-year-old children with Down syndrome. J Neurodev Disord. 2022 Mar 12;14(1):18. doi: 10.1186/s11689-022-09430-4.

Silverman JL, Thurm A, Ethridge SB, Soller MM, Petkova SP, Abel T, Bauman MD, Brodkin ES, Harony-Nicolas H, Wöhr M, Halladay A. Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future. Genes Brain Behav. 2022 Mar 14:e12803. doi: 10.1111/gbb.12803.

Smucny J, Vlasova RM, Lesh TA, Rowland DJ, Wang G, Chaudhari AJ, Chen S, Iosif AM, Hogrefe CE, Bennett JL, Shumann CM, Van de Water JA, Maddock RJ, Styner MA, Geschwind DH, McAllister AK, Bauman MD, Carter CS. Increased Striatal Presynaptic Dopamine in a Nonhuman Primate Model of Maternal Immune Activation: A Longitudinal Neurodevelopmental Positron Emission Tomography Study With Implications for Schizophrenia. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Nov 17:S2451-9022(22)00277-4. doi: 10.1016/j.bpsc.2022.10.012.

Soltani A, Schworer EK, Jacobson LA, Channell MM, Lee NR, Faught GG, Grzadzinski R, Fidler D, Esbensen AJ. Confirmatory factor analysis of the BRIEF2 in a sample of youth with Down syndrome. J Intellect Disabil Res. 2022 Dec 26. doi: 10.1111/jir.13000.

Talbott MR, Lang E, Avila F, Dufek S, Young G. Short report: Experiences of Caregivers Participating in a Telehealth Evaluation of Development for Infants (TEDI). J Autism Dev Disord. 2022 Dec;52(12):5266-5273. doi: 10.1007/s10803-022-05607-x.

Thurman AJ, Swinehart SS, Klusek J, Roberts JE, Bullard L, Marzan JCB, Brown WT, Abbeduto L. Daily Living Skills in Adolescent and Young Adult Males With Fragile X Syndrome. Am J Intellect Dev Disabil. 2022 Jan 1;127(1):64-83. doi: 10.1352/1944-7558-127.1.64.

Thurman AJ, Bullard L, Kelly L, Wong C, Nguyen V, Esbensen AJ, Bekins J, Schworer EK, Fidler DJ, Daunhauer LA, Mervis CB, Pitts CH, Becerra AM, Abbeduto L. Defining Expressive Language Benchmarks for Children with Down Syndrome. Brain Sci. 2022 Jun 6;12(6):743. doi: 10.3390/brainsci12060743.

Thurman AJ, Dimachkie Nunnally A. Joint attention performance in preschool-aged boys with autism or fragile X syndrome. Front Psychol. 2022 Aug 8;13:918181. doi: 10.3389/fpsyg.2022.918181.

Van Deusen K, Prince MA, Esbensen AJ, Edgin JO, Schworer EK, Thurman AJ, Patel LR, Daunhauer LA, Fidler DJ. Profiles of Caregiver-Reported Executive Function in Children with Down Syndrome. Brain Sci. 2022 Oct 1;12(10):1333. doi: 10.3390/brainsci12101333.

Waizbard-Bartov E, Ferrer E, Heath B, Rogers SJ, Nordahl CW, Solomon M, Amaral DG. Identifying autism symptom severity trajectories across childhood. Autism Res. 2022 Jan 27. doi: 10.1002/aur.2674.

Wang JY, Grigsby J, Placido D, Wei H, Tassone F, Kim K, Hessl D, Rivera SM, Hagerman RJ. Clinical and Molecular Correlates of Abnormal Changes in the Cerebellum and Globus Pallidus in Fragile X Premutation. Front Neurol. 2022 Feb 8;13:797649. doi: 10.3389/fneur.2022.797649.

Wilson MD, Ponzini MD, Taylor SL, Kim K. Imputation of Missing Values for Multi-Biospecimen Metabolomics Studies: Bias and Effects on Statistical Validity. Metabolites. 2022 Jul 21;12(7):671. doi: 10.3390/metabo12070671.

Winder-Patel B, Tudor ME, Kerns CM, Davis K, Nordahl CW, Amaral DG, Solomon M. Often Undiagnosed but Treatable: Case Vignettes and Clinical Considerations for Assessing Anxiety Disorders in Youth with Autism Spectrum Disorder and Intellectual Disability. Evid Based Pract Child Adolesc Ment Health. 2022;7(1):24-40. doi: 10.1080/23794925.2021.1923090.

Zhu Y, Gomez JA, Laufer BI, Mordaunt CE, Mouat JS, Soto DC, Dennis MY, Benke KS, Bakulski KM, Dou J, Marathe R, Jianu JM, Williams LA, Gutierrez Fugón OJ, Walker CK, Ozonoff S, Daniels J, Grosvenor LP, Volk HE, Feinberg JI, Fallin MD, Hertz-Picciotto I, Schmidt RJ, Yasui DH, LaSalle JM. Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism. Genome Biol. 2022 Feb 16;23(1):46. doi: 10.1186/s13059-022-02613-1.

2021

Abbeduto L, Klusek J, Taylor JL, Abdelnur N, Sparapani N, Thurman AJ. Concurrent Associations between Expressive Language Ability and Independence in Adolescents and Adults with Fragile X Syndrome.  Brain Sci. 2021 Sep 8;11(9):1179. doi: 10.3390/brainsci11091179.

Abbeduto L, Sahin M. Developing and evaluating treatments for the challenges of autism and related neurodevelopmental disabilities. J Neurodev Disord. 2021 Nov 17;13(1):56. doi: 10.1186/s11689-021-09404-y.

Adhikari A, Copping NA, Beegle J, Cameron DL, Deng P, O'Geen H, Segal DJ, Fink KD, Silverman JL, Anderson JS. Functional rescue in an Angelman syndrome model following treatment with lentivector transduced hematopoietic stem cells.  Hum Mol Genet. 2021 Jun 9;30(12):1067-1083. doi: 10.1093/hmg/ddab104.

Amina S, Falcone C, Hong T, Wolf-Ochoa MW, Vakilzadeh G, Allen E, Perez-Castro R, Kargar M, Noctor S, Martínez-Cerdeño V. Chandelier Cartridge Density Is Reduced in the Prefrontal Cortex in Autism.  Cereb Cortex. 2021 May 10;31(6):2944-2951. doi: 10.1093/cercor/bhaa402.

Andrews DS, Lee JK, Harvey DJ, Waizbard-Bartov E, Solomon M, Rogers SJ, Nordahl CW, Amaral DG. A Longitudinal Study of White Matter Development in Relation to Changes in Autism Severity Across Early Childhood.  2021 Mar 1;89(5):424-432. doi: 10.1016/j.biopsych.2020.10.013.

Barkoski JM, Philippat C, Tancredi D, Schmidt RJ, Ozonoff S, Barr DB, Elms W, Bennett DH, Hertz-Picciotto I. In utero pyrethroid pesticide exposure in relation to autism spectrum disorder (ASD) and other neurodevelopmental outcomes at 3 years in the MARBLES longitudinal cohort.  Environ Res. 2021 Mar;194:110495. doi: 10.1016/j.envres.2020.110495.

Berg EL, Petkova SP, Born HA, Adhikari A, Anderson AE, Silverman JL. Insulin-like growth factor-2 does not improve behavioral deficits in mouse and rat models of Angelman Syndrome.  Mol Autism. 2021 Sep 15;12(1):59. doi: 10.1186/s13229-021-00467-1.

Bullard L, Harvey D, Abbeduto L. Exploring the feasibility of collecting multimodal multiperson assessment data via distance in families affected by fragile X syndrome.  J Telemed Telecare. 2021 Apr 12:1357633X211003810. doi: 10.1177/1357633X211003810.

Bullard L, Harvey D, Abbeduto L. Maternal Mental Health and Parenting Stress and Their Relationships to Characteristics of the Child With Fragile X Syndrome. Front Psychiatry. 2021 Nov 24;12:716585. doi: 10.3389/fpsyt.2021.716585

Calsbeek JJ, González EA, Boosalis CA, Zolkowska D, Bruun DA, Rowland DJ, Saito NH, Harvey DJ, Chaudhari AJ, Rogawski MA, Garbow JR, Lein PJ. Strain differences in the extent of brain injury in mice after tetramethylenedisulfotetramine-induced status epilepticus. Neurotoxicology. 2021 Dec;87:43-50. doi: 10.1016/j.neuro.2021.08.011.

Calsbeek JJ, González EA, Bruun DA, Guignet MA, Copping N, Dawson ME, Yu AJ, MacMahon JA, Saito NH, Harvey DJ, Silverman JL, Lein PJ. Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate. Neurotoxicology. 2021 Dec;87:106-119. doi: 10.1016/j.neuro.2021.09.001.

Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia M, Dunlap LE, Rabow ZT, Fiehn O, Wulff H, McCorvy JD, Lein PJ, Kokel D, Ron D, Peters J, Zuo Y, Olson DE. A non-hallucinogenic psychedelic analogue with therapeutic potential.  Nature. 2021 Jan;589(7842):474-479. doi: 10.1038/s41586-020-3008-z.

Copping NA, Silverman JL. Abnormal electrophysiological phenotypes and sleep deficits in a mouse model of Angelman Syndrome.  Mol Autism. 2021 Feb 6;12(1):9. doi: 10.1186/s13229-021-00416-y.

Dahlenburg H, Cameron D, Yang S, Bachman A, Pollock K, Cary W, Pham M, Hendrix K, White J, Nelson H, Deng P, Anderson JS, Fink K, Nolta J.  A novel Huntington's disease mouse model to assess the role of neuroinflammation on disease progression and to develop human cell therapies.  Stem Cells Transl Med. 2021 Jul;10(7):1033-1043. doi: 10.1002/sctm.20-0431.

Del Hoyo Soriano L, Bullard L, Thurman AJ, Alvarez CH, Abbeduto L.  Providing a parent-administered outcome measure in a bilingual family of a father and a mother of two adolescents with ASD: brief report.  Dev Neurorehabil. 2021 Jun 25:1-5. doi: 10.1080/17518423.2021.1942281.

Del Hoyo Soriano L, Rosser TC, Hamilton DR, Harvey DJ, Abbeduto L, Sherman SL. Relationship between Apgar scores and long-term cognitive outcomes in individuals with Down syndrome.  Sci Rep. 2021 Jun 16;11(1):12707. doi: 10.1038/s41598-021-90651-3.

Dong C, Ly C, Dunlap LE, Vargas MV, Sun J, Hwang IW, Azinfar A, Oh WC, Wetsel WC, Olson DE, Tian L. Psychedelic-inspired drug discovery using an engineered biosensor.  Cell. 2021 May 13;184(10):2779-2792.e18. doi: 10.1016/j.cell.2021.03.043.

Ellegood J, Petkova SP, Kinman A, Qiu LR, Adhikari A, Wade AA, Fernandes D, Lindenmaier Z, Creighton A, Nutter LMJ, Nord AS, Silverman JL, Lerch JP. Neuroanatomy and behavior in mice with a haploinsufficiency of AT-rich interactive domain 1B (ARID1B) throughout development.  Mol Autism. 2021 Mar 23;12(1):25. doi: 10.1186/s13229-021-00432-y.

Ezzati A, Abdulkadir A, Jack CR Jr, Thompson PM, Harvey DJ, Truelove-Hill M, Sreepada LP, Davatzikos C; Alzheimer's Disease Neuroimaging Initiative, Lipton RB. Predictive value of ATN biomarker profiles in estimating disease progression in Alzheimer's disease dementia. Alzheimers Dement. 2021 Nov;17(11):1855-1867. doi: 10.1002/alz.12491.

Grzadzinski R, Amso D, Landa R, Watson L, Guralnick M, Zwaigenbaum L, Deák G, Estes A, Brian J, Bath K, Elison J, Abbeduto L, Wolff J, Piven J. Pre-symptomatic intervention for autism spectrum disorder (ASD): defining a research agenda.  J Neurodev Disord. 2021 Oct 15;13(1):49. doi: 10.1186/s11689-021-09393-y.

Hagerman R, Hagerman P. Fragile X-associated tremor/ataxia syndrome: pathophysiology and management.  Curr Opin Neurol. 2021 Aug 1;34(4):541-546. doi: 10.1097/WCO.0000000000000954.

Haigh JL, Adhikari A, Copping NA, Stradleigh T, Wade AA, Catta-Preta R, Su-Feher L, Zdilar I, Morse S, Fenton TA, Nguyen A, Quintero D, Agezew S, Sramek M, Kreun EJ, Carter J, Gompers A, Lambert JT, Canales CP, Pennacchio LA, Visel A, Dickel DE, Silverman JL, Nord AS. Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice.  Genome Med. 2021 Apr 26;13(1):69. doi: 10.1186/s13073-021-00884-0.

Hennessey C, Keogh CE, Barboza M, Brust-Mascher I, Knotts TA, Sladek JA, Pusceddu MM, Stokes P, Rabasa G, Honeycutt M, Walsh O, Nichols R, Reardon C, Gareau MG. Neonatal Enteropathogenic Escherichia coli Infection Disrupts Microbiota-Gut-Brain Axis Signaling.  Infect Immun. 2021 Aug 16;89(9):e0005921. doi: 10.1128/IAI.00059-21.

Hessl D, Libero L, Schneider A, Kerns C, Winder-Patel B, Heath B, Lee J, Coleman C, Sharma N, Solomon M, Nordahl CW, Amaral DG. Fear Potentiated Startle in Children With Autism Spectrum Disorder: Association With Anxiety Symptoms and Amygdala Volume.  Autism Res. 2021 Mar;14(3):450-463. doi: 10.1002/aur.2460.

Holm KN, Herren AW, Taylor SL, Randol JL, Kim K, Espinal G, Martiínez-Cerdeño V, Pessah IN, Hagerman RJ, Hagerman PJ. Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome. Front Mol Biosci. 2021 Jan 29;7:600840. doi: 10.3389/fmolb.2020.600840.

Hughes HK, Mills-Ko E, Yang H, Lesh TA, Carter CS, Ashwood P. Differential Macrophage Responses in Affective Versus Non-Affective First-Episode Psychosis Patients. Front Cell Neurosci. 2021 Feb 24;15:583351. doi: 10.3389/fncel.2021.583351.

Kaat AJ, McKenzie FJ, Shields RH, LaForte E, Coleman J, Michalak C, Hessl DR. Assessing processing speed among individuals with intellectual and developmental disabilities: A match-to-sample paradigm. Child Neuropsychol. 2021 Jun 14:1-13. doi: 10.1080/09297049.2021.1938987.

Keil Stietz KP, Kennedy CL, Sethi S, Valenzuela A, Nunez A, Wang K, Wang Z, Wang P, Spiegelhoff A, Puschner B, Bjorling DE, Lein PJ. In utero and lactational PCB exposure drives anatomic changes in the juvenile mouse bladder. Curr Res Toxicol. 2021;2:1-18. doi: 10.1016/j.crtox.2021.01.002.

Kim K, Shin HM, Busgang SA, Barr DB, Panuwet P, Schmidt RJ, Hertz-Picciotto I, Bennett DH. Temporal Trends of Phenol, Paraben, and Triclocarban Exposure in California Pregnant Women during 2007-2014. Environ Sci Technol. 2021 Aug 17;55(16):11155-11165. doi: 10.1021/acs.est.1c01564.

Klusek J, Thurman AJ, Abbeduto L. Maternal Pragmatic Language Difficulties in the FMR1 Premutation and the Broad Autism Phenotype: Associations with Individual and Family Outcomes. J Autism Dev Disord. 2021 Apr 4. doi: 10.1007/s10803-021-04980-3.

Lee JK, Andrews DS, Ozonoff S, Solomon M, Rogers S, Amaral DG, Nordahl CW. Longitudinal Evaluation of Cerebral Growth Across Childhood in Boys and Girls With Autism Spectrum Disorder. Biol Psychiatry. 2020 Nov 3:S0006-3223(20)32023-0. doi: 10.1016/j.biopsych.2020.10.014.

Linton SR, Popa AM, Luck SJ, Bolden K, Angkustsiri K, Carter CS, Niendam TA, Simon TJ. Atypical attentional filtering of visual information in youth with chromosome 22q11.2 deletion syndrome as indexed by event-related potentials. Neuroimage Clin. 2021 Nov 9;32:102877. doi: 10.1016/j.nicl.2021.102877.

Lovos A, Bottrill K, Sakhon S, Nyhuis C, Egleson E, Luongo A, Murphy M, Thurman AJ, Abbeduto L, Lee NR, Hughes K, Edgin J. Circadian Sleep-Activity Rhythm across Ages in Down Syndrome. Brain Sci. 2021 Oct 25;11(11):1403. doi: 10.3390/brainsci11111403.

Matelski L, Keil Stietz KP, Sethi S, Taylor SL, Van de Water J, Lein PJ. The influence of sex, genotype, and dose on serum and hippocampal cytokine levels in juvenile mice developmentally exposed to a human-relevant mixture of polychlorinated biphenyls. Curr Res Toxicol. 2020 Jun 10;1:85-103. doi: 10.1016/j.crtox.2020.09.001.

Miller M, Sun S, Iosif AM, Young GS, Belding A, Tubbs A, Ozonoff S. Repetitive behavior with objects in infants developing autism predicts diagnosis and later social behavior as early as 9 months. J Abnorm Psychol. 2021 Aug;130(6):665-675. doi: 10.1037/abn0000692.

Moser C, Mattie L, Abbeduto L, Klusek J. The FMR1 Premutation Phenotype and Mother-Youth Synchrony in Fragile X Syndrome. Am J Intellect Dev Disabil. 2021 Nov 1;126(6):443-459. doi: 10.1352/1944-7558-126.6.443.

Mukherjee P, Hartanto T, Iosif AM, Dixon JF, Hinshaw SP, Pakyurek M, van den Bos W, Guyer AE, McClure SM, Schweitzer JB, Fassbender C. Neural basis of working memory in ADHD: Load versus complexity. Neuroimage Clin. 2021;30:102662. doi: 10.1016/j.nicl.2021.102662.

Neier K, Grant TE, Palmer RL, Chappell D, Hakam SM, Yasui KM, Rolston M, Settles ML, Hunter SS, Madany A, Ashwood P, Durbin-Johnson B, LaSalle JM, Yasui DH. Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome. Commun Biol. 2021 Dec 16;4(1):1408. doi: 10.1038/s42003-021-02915-3.

Oh J, Bennett DH, Calafat AM, Tancredi D, Roa DL, Schmidt RJ, Hertz-Picciotto I, Shin HM. Prenatal exposure to per- and polyfluoroalkyl substances in association with autism spectrum disorder in the MARBLES study.   Environ Int. 2021 Feb;147:106328. doi: 10.1016/j.envint.2020.106328.

Penna E, Cunningham CL, Saylor S, Kreutz A, Tarantal AF, Martínez-Cerdeño V, Noctor SC. Greater Number of Microglia in Telencephalic Proliferative Zones of Human and Nonhuman Primate Compared with Other Vertebrate Species. Cereb Cortex Commun. 2021 Sep 6;2(4):tgab053. doi: 10.1093/texcom/tgab053

Ramirez-Celis A, Becker M, Nuño M, Schauer J, Aghaeepour N, Van de Water J. Risk assessment analysis for maternal autoantibody-related autism (MAR-ASD): a subtype of autism. Mol Psychiatry. 2021 May;26(5):1551-1560. doi: 10.1038/s41380-020-00998-8.

Reetzke R, Iosif AM, Hatch B, de la Paz L, Chuang A, Ozonoff S, Miller M. Patterns of objectively measured motor activity among infants developing ASD and concerns for ADHD. J Child Psychol Psychiatry. 2021 Aug 13. doi: 10.1111/jcpp.13504.

Rogers SJ, Yoder P, Estes A, Warren Z, McEachin J, Munson J, Rocha M, Greenson J, Wallace L, Gardner E, Dawson G, Sugar CA, Hellemann G, Whelan F. A Multisite Randomized Controlled Trial Comparing the Effects of Intervention Intensity and Intervention Style on Outcomes for Young Children With Autism. J Am Acad Child Adolesc Psychiatry. 2021 Jun;60(6):710-722. doi: 10.1016/j.jaac.2020.06.013.

Salcedo-Arellano MJ, Wang JY, McLennan YA, Doan M, Cabal-Herrera AM, Jimenez S, Wolf-Ochoa MW, Sanchez D, Juarez P, Tassone F, Durbin-Johnson B, Hagerman RJ, Martínez-Cerdeño V. Cerebral Microbleeds in Fragile X-Associated Tremor/Ataxia Syndrome. Mov Disord. 2021 Mar 24. doi: 10.1002/mds.28559.

Sekar A, Sanches TM, Hino K, Kumar M, Wang J, Ha E, Durbin-Johnson B, Simó S, Dennis MY. RapID Cell Counter: Semi-Automated and Mid-Throughput Estimation of Cell Density within Diverse Cortical Layers. eNeuro. 2021 Nov 30;8(6):ENEURO.0185-21.2021. doi: 10.1523/ENEURO.0185-21.2021. Print 2021 Nov-Dec.

Sethi S, Keil Stietz KP, Valenzuela AE, Klocke CR, Silverman JL, Puschner B, Pessah IN, Lein PJ.. Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium. Front Neurosci. 2021 Dec 6;15:766826. doi: 10.3389/fnins.2021.766826.

Shew CJ, Carmona-Mora P, Soto DC, Mastoras M, Roberts E, Rosas J, Jagannathan D, Kaya G, O'Geen H, Dennis MY. Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes. Mol Biol Evol. 2021 Jul 29;38(8):3060-3077. doi: 10.1093/molbev/msab131.

Shin HM, Oh J, Kim K, Busgang SA, Barr DB, Panuwet P, Schmidt RJ, Hertz-Picciotto I, Bennett DH. Variability of Urinary Concentrations of Phenols, Parabens, and Triclocarban during Pregnancy in First Morning Voids and Pooled Samples. Environ Sci Technol. 2021 Dec 7;55(23):16001-16010. doi: 10.1021/acs.est.1c04140.

Soriano LDH, Bullard L, Alvarez CH, Thurman AJ, Abbeduto L. Using telehealth-delivered procedures to collect a parent-implemented expressive language sampling narrative task in monolingual and bilingual families with Autism Spectrum Disorder: A pilot study. Front Rehabilit Sci. 2021 Nov;2:716550. doi: 10.3389/fresc.2021.716550

Talbott MR, Dufek S, Young G, Rogers SJ. Leveraging telehealth to evaluate infants with prodromal autism spectrum disorder characteristics using the telehealth evaluation of development for infants. Autism. 2021 Sep 22:13623613211045596. doi: 10.1177/13623613211045596.

Tassanakijpanich N, McKenzie FJ, McLennan YA, Makhoul E, Tassone F, Jasoliya MJ, Romney C, Petrasic IC, Napalinga K, Buchanan CB, Hagerman P, Hagerman R, Casanova EL. Hypermobile Ehlers-Danlos syndrome (hEDS) phenotype in fragile X premutation carriers: case series. J Med Genet. 2021 Jun 30:jmedgenet-2020-107609. doi: 10.1136/jmedgenet-2020-107609.

Taylor S, Ponzini M, Wilson M, Kim K. Comparison of imputation and imputation-free methods for statistical analysis of mass spectrometry data with missing data .  Brief Bioinform. 2021 Sep 1:bbab353. doi: 10.1093/bib/bbab353.

Thurman AJ, Edgin JO, Sherman SL, Sterling A, McDuffie A, Berry-Kravis E, Hamilton D, Abbeduto L. Spoken language outcome measures for treatment studies in Down syndrome: feasibility, practice effects, test-retest reliability, and construct validity of variables generated from expressive language sampling.   J Neurodev Disord. 2021 Apr 8;13(1):13. doi: 10.1186/s11689-021-09361-6.

Toedebusch R, Grodzki AC, Dickinson PJ, Woolard K, Vinson N, Sturges B, Snyder J, Li CF, Nagasaka O, Consales B, Vernau K, Knipe M, Murthy V, Lein PJ, Toedebusch CM. Glioma-associated microglia/macrophages augment tumorigenicity in canine astrocytoma, a naturally occurring model of human glioma.   Neurooncol Adv. 2021 May 4;3(1):vdab062. doi: 10.1093/noajnl/vdab062.

Wang J, Napoli E, Kim K, McLennan YA, Hagerman RJ, Giulivi C. Brain Atrophy and White Matter Damage Linked to Peripheral Bioenergetic Deficits in the Neurodegenerative Disease FXTAS.   Int J Mol Sci. 2021 Aug 25;22(17):9171. doi: 10.3390/ijms22179171.

vonderEmbse AN, Elmore SE, Jackson KB, Habecker BA, Manz KE, Pennell KD, Lein PJ, La Merrill MA. Developmental exposure to DDT or DDE alters sympathetic innervation of brown adipose in adult female mice.   Environ Health. 2021 Apr 1;20(1):37. doi: 10.1186/s12940-021-00721-2.

2020

Abbeduto L. Presidential Address, 2020-Using Technology to Deliver Services and Supports in Homes, Neighborhoods, and Communities: Evidence and Promise.  Intellect Dev Disabil. 2020 Dec 1;58(6):525-531. doi: 10.1352/1934-9556-58.6.525.

Abbeduto L, Berry-Kravis E, Sterling A, Sherman S, Edgin JO, McDuffie A, Hoffmann A, Hamilton D, Nelson M, Aschkenasy J, Thurman AJ. Expressive language sampling as a source of outcome measures for treatment studies in fragile X syndrome: feasibility, practice effects, test-retest reliability, and construct validity.  Neurodev Disord. 2020 Mar 24;12(1):10. doi: 10.1186/s11689-020-09313-6.

Ashley K, Steinfeld MB, Young GS, Ozonoff S. Onset, Trajectory, and Pattern of Feeding Difficulties in Toddlers Later Diagnosed with Autism.   J Dev Behav Pediatr. 2020 Apr;41(3):165-171. doi: 10.1097/DBP.0000000000000757.

Bauman MD, Van de Water J. Translational opportunities in the prenatal immune environment: Promises and limitations of the maternal immune activation model.  Neurobiol Dis. 2020 Jul;141:104864. doi: 10.1016/j.nbd.2020.104864.

Berg EL, Ching TM, Bruun DA, Rivera JK, Careaga M, Ellegood J, Lerch JP, Wöhr M, Lein PJ, Silverman JL. Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos.  J Neurodev Disord. 2020 Dec 16;12(1):40. doi: 10.1186/s11689-020-09342-1.

Berg EL, Pedersen LR, Pride MC, Petkova SP, Patten KT, Valenzuela AE, Wallis C, Bein KJ, Wexler A, Lein PJ, Silverman JL. Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats.  Transl Psychiatry. 2020 Aug 17;10(1):289. doi: 10.1038/s41398-020-00978-0.

Berg EL, Pride MC, Petkova SP, Lee RD, Copping NA, Shen Y, Adhikari A, Fenton TA, Pedersen LR, Noakes LS, Nieman BJ, Lerch JP, Harris S, Born HA, Peters MM, Deng P, Cameron DL, Fink KD, Beitnere U, O'Geen H, Anderson AE, Dindot SV, Nash KR, Weeber EJ, Wöhr M, Ellegood J, Segal DJ, Silverman JL. Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome.   Transl Psychiatry. 2020 Jan 27;10(1):39. doi: 10.1038/s41398-020-0720-2.

Cabal-Herrera AM, Tassanakijpanich N, Salcedo-Arellano MJ, Hagerman RJ.  Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS): Pathophysiology and Clinical Implications.  Int J Mol Sci. 2020 Jun 20;21(12):E4391. doi: 10.3390/ijms21124391.

Channell MM.  Cross-Sectional Trajectories of Mental State Language Development in Children With Down Syndrome.  Am J Speech Lang Pathol. 2020 May 8;29(2):760-775. doi: 10.1044/2020_AJSLP-19-00035.

Colón-Rodríguez A, Uribe-Salazar JM, Weyenberg KB, Sriram A, Quezada A, Kaya G, Jao E, Radke B, Lein PJ, Dennis MY.  Assessment of Autism Zebrafish Mutant Models Using a High-Throughput Larval Phenotyping Platform. Front Cell Dev Biol. 2020 Nov 23;8:586296. doi: 10.3389/fcell.2020.586296.

Del Hoyo Soriano L, Thurman AJ, Harvey D, Kover ST, Abbeduto L.  Expressive language development in adolescents with Down syndrome and fragile X syndrome: change over time and the role of family-related factors. J Neurodev Disord. 2020 Jun 27;12(1):18. doi: 10.1186/s11689-020-09320-7.

Del Hoyo Soriano L, Rosser T, Hamilton D, Wood T, Abbeduto L, Sherman S.  Gestational age is related to symptoms of attention-deficit/hyperactivity disorder in late-preterm to full-term children and adolescents with down syndrome. Sci Rep. 2020 Nov 23;10(1):20345. doi: 10.1038/s41598-020-77392-5.

Dufour BD, Amina S, Martinez-Cerdeno V.  FXTAS presents with upregulation of the cytokines IL12 and TNFα. Parkinsonism Relat Disord. 2020 Nov 30;82:117-120. doi: 10.1016/j.parkreldis.2020.11.026.

Dunlap LE, Azinfar A, Ly C, Cameron LP, Viswanathan J, Tombari RJ, Myers-Turnbull D, Taylor JC, Grodzki AC, Lein PJ, Kokel D, Olson DE. Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies. J Med Chem. 2020 Feb 13;63(3):1142-1155. doi: 10.1021/acs.jmedchem.9b01404.

Estes ML, Prendergast K, MacMahon JA, Cameron S, Paul Aboubechara J, Farrelly K, Sell GL, Haapanen L, Schauer JD, Horta A, Shaffer IC, Le CT, Kincheloe GN, Tan DJ, van der List D, Bauman MD, Carter CS, Van de Water J, McAllister AK. Baseline immunoreactivity before pregnancy and poly(I:C) dose combine to dictate susceptibility and resilience of offspring to maternal immune activation. Brain Behav Immun. 2020 Aug;88:619-630. doi: 10.1016/j.bbi.2020.04.061

Finestack LH, Rohwer B, Hilliard L, Abbeduto L. Using Computerized Language Analysis to Evaluate Grammatical Skills.  Lang Speech Hear Serv Sch. 2020 Apr 7;51(2):184-204. doi: 10.1044/2019_LSHSS-19-00032.

Gangi DN, Boterberg S, Schwichtenberg AJ, Solis E, Young GS, Iosif AM, Ozonoff S. Declining Gaze to Faces in Infants Developing Autism Spectrum Disorder: Evidence From Two Independent Cohorts. Child Dev. 2020 Dec 8. doi: 10.1111/cdev.13471.

González EA, Rindy AC, Guignet MA, Calsbeek JJ, Bruun DA, Dhir A, Andrew P, Saito N, Rowland DJ, Harvey DJ, Rogawski MA, Lein PJ. The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity. Arch Toxicol. 2020 Apr 18. doi: 10.1007/s00204-020-02747-w.

Hatch B, Iosif AM, Chuang A, de la Paz L, Ozonoff S, Miller M. Longitudinal Differences in Response to Name Among Infants Developing ASD and Risk for ADHD.  J Autism Dev Disord. 2020 Jan 23. doi: 10.1007/s10803-020-04369-8.

Hatch B, Nordahl CW, Schwichtenberg AJ, Ozonoff S, Miller M. Factor Structure of the Children's Sleep Habits Questionnaire in Young Children with and Without Autism.  J Autism Dev Disord. 2020 Nov 12. doi: 10.1007/s10803-020-04752-5.

Hennebelle M, Morgan RK, Sethi S, Zhang Z, Chen H, Grodzki AC, Lein PJ, Taha AY. Linoleic acid-derived metabolites constitute the majority of oxylipins in the rat pup brain and stimulate axonal growth in primary rat cortical neuron-glia co-cultures in a sex-dependent manner.  J Neurochem. 2020 Jan;152(2):195-207. doi: 10.1111/jnc.14818.

Hessl D, Libero L, Schneider A, Kerns C, Winder-Patel B, Heath B, Lee J, Coleman C, Sharma N, Solomon M, Nordahl CW, Amaral DG. Fear Potentiated Startle in Children With Autism Spectrum Disorder: Association With Anxiety Symptoms and Amygdala Volume.  Autism Res. 2020 Dec 29. doi: 10.1002/aur.2460.

Hill MM, Gangi D, Miller M, Rafi SM, Ozonoff S. Screen time in 36-month-olds at increased likelihood for ASD and ADHD.  Infant Behav Dev. 2020 Nov;61:101484. doi: 10.1016/j.infbeh.2020.101484.

Jasoliya M, Bowling H, Petrasic IC, Durbin-Johnson B, Klann E, Bhattacharya A, Hagerman R, Tassone F.Jasoliya M, et al. Blood-Based Biomarkers Predictive of Metformin Target Engagement in Fragile X Syndrome. Brain Sci. 2020 Jun 10;10(6):E361. doi: 10.3390/brainsci10060361.Brain Sci. 2020.

Jones KL, Pride MC, Edmiston E, Yang M, Silverman JL, Crawley JN, Van de Water J. Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism. Mol Psychiatry. 2020 Nov;25(11):2994-3009. doi: 10.1038/s41380-018-0126-1.

Kahle S, Mukherjee P, Dixon JF, Leibenluft E, Hinshaw SP, Schweitzer JB. Irritability Predicts Hyperactive/Impulsive Symptoms Across Adolescence for Females. Res Child Adolesc Psychopathol. 2020 Nov 27. doi: 10.1007/s10802-020-00723-7.

Kerns CM, Winder-Patel B, Iosif AM, Nordahl CW, Heath B, Solomon M, Amaral DG. Clinically Significant Anxiety in Children with Autism Spectrum Disorder and Varied Intellectual Functioning. J Clin Child Adolesc Psychol. 2020 Jan 23:1-16. doi: 10.1080/15374416.2019.1703712.

Linton SR, Popa AM, Luck SJ, Bolden K, Carter CS, Niendam TA, Simon TJ. Neural and behavioral measures suggest that cognitive and affective functioning interactions mediate risk for psychosis-proneness symptoms in youth with chromosome 22q11.2 deletion syndrome.  Am J Med Genet A. 2020 Apr 22. doi: 10.1002/ajmg.a.61596.

Ly C, Shimizu AJ, Vargas MV, Duim WC, Wender PA, Olson DE. Bryostatin 1 Promotes Synaptogenesis and Reduces Dendritic Spine Density in Cortical Cultures through a PKC-Dependent Mechanism.   ACS Chem Neurosci. 2020 Jun 3;11(11):1545-1554. doi: 10.1021/acschemneuro.0c00175

Lyall K, Song L, Botteron K, Croen LA, Dager SR, Fallin MD, Hazlett HC, Kauffman E, Landa R, Ladd-Acosta C, Messinger DS, Ozonoff S, Pandey J, Piven J, Schmidt RJ, Schultz RT, Stone WL, Newschaffer CJ, Volk HE. The Association Between Parental Age and Autism-Related Outcomes in Children at High Familial Risk for Autism.   Autism Res. 2020 Apr 21. doi: 10.1002/aur.2303.

Matelski L, Morgan RK, Grodzki AC, Van de Water J, Lein PJ. Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line.  Mol Psychiatry. 2020 Jan 21. doi: 10.1038/s41380-020-0647-2.

McKenzie FJ, Tassankijpanich N, Epps KC, March SK, Hagerman RJ. Spontaneous Coronary Artery Dissection in Females With the Fragile X FMR1 Premutation.  JACC Case Rep. 2020 Jan;2(1):40-44. doi: 10.1016/j.jaccas.2019.11.058

Miller M, Iosif AM, Bell LJ, Farquhar-Leicester A, Hatch B, Hill A, Hill MM, Solis E, Young GS, Ozonoff S. Can Familial Risk for ADHD Be Detected in the First Two Years of Life?   J Clin Child Adolesc Psychol. 2020 Jan 17:1-13. doi: 10.1080/15374416.2019.1709196.

Mordaunt CE, Jianu JM, Laufer BI, Zhu Y, Hwang H, Dunaway KW, Bakulski KM, Feinberg JI, Volk HE, Lyall K, Croen LA, Newschaffer CJ, Ozonoff S, Hertz-Picciotto I, Fallin MD, Schmidt RJ, LaSalle JM. Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes.   Genome Med. 2020 Oct 14;12(1):88. doi: 10.1186/s13073-020-00785-8.

Napoli E, McLennan YA, Schneider A, Tassone F, Hagerman RJ, Giulivi C. Characterization of the Metabolic, Clinical and Neuropsychological Phenotype of Female Carriers of the Premutation in the X-Linked FMR1 Gene. Front Mol Biosci. 2020 Oct 22;7:578640. doi: 10.3389/fmolb.2020.578640.

Nordahl CW, Iosif AM, Young GS, Hechtman A, Heath B, Lee JK, Libero L, Reinhardt VP, Winder-Patel B, Amaral DG, Rogers S, Solomon M, Ozonoff S. High Psychopathology Subgroup in Young Children With Autism: Associations With Biological Sex and Amygdala Volume.  J Am Acad Child Adolesc Psychiatry. 2020 Jan 20:S0890-8567(20)30018-6. doi: 10.1016/j.jaac.2019.11.022.

Panesar HK, Kennedy CL, Keil Stietz KP, Lein PJ. Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder? Toxics. 2020 Sep 17;8(3):E70. doi: 10.3390/toxics8030070.

Parikh C, Iosif AM, Ozonoff S. Brief Report: Use of the Infant-Toddler Checklist in Infant Siblings of Children with Autism Spectrum Disorder.   J Autism Dev Disord. 2020 Mar 26. doi: 10.1007/s10803-020-04468-6.

Patten KT, González EA, Valenzuela A, Berg E, Wallis C, Garbow JR, Silverman JL, Bein KJ, Wexler AS, Lein PJ. Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats.   Transl Psychiatry. 2020 May 27;10(1):166. doi: 10.1038/s41398-020-0845-3.

Petkova SP, Pride M, Klocke C, Fenton TA, White J, Lein PJ, Ellegood J, Lerch JP, Silverman JL, Waldau B. Cyclin D2-knock-out mice with attenuated dentate gyrus neurogenesis have robust deficits in long-term memory formation.   Sci Rep. 2020 May 18;10(1):8204. doi: 10.1038/s41598-020-65090-1

Rajaratnam A, Potter LA, Biag HMB, Schneider A, Petrasic IC, Hagerman RJ. Review of Autism Profiles and Response to Sertraline in Fragile X Syndrome-Associated Autism vs. Non-syndromic Autism; Next Steps for Targeted Treatment.   Font Neurol. 2020 Oct 30;11:581429. doi: 10.3389/fneur.2020.581429.

Ramirez-Celis A, Edmiston E, Schauer J, Vu T, Van de Water J. Peptides of neuron specific enolase as potential ASD biomarkers: From discovery to epitope mapping.   Brain Behav Immun. 2020 Feb;84:200-208. doi: 10.1016/j.bbi.2019.12.002.

Restrepo Bibiana, Angkustsiri Kathleen, Taylor Sandra L, Rogers Sally J, Cabral Jacqueline, Heath Brianna, Hechtman Alexa, Solomon Marjorie, Ashwood Paul, Amaral David G, Nordahl Christine Wu. Developmental-behavioral profiles in children with autism spectrum disorder and co-occurring gastrointestinal symptoms  Autism Res. 2020 Aug 6. doi: 10.1002/aur.2354.

Ryan AM, Murai T, Lau AR, Hogrefe CE, McAllister AK, Carter CS, Bauman MD. New approaches to quantify social development in rhesus macaques (Macaca mulatta): Integrating eye tracking with traditional assessments of social behavior.  Dev Psychobiol. 2020 Jul 14. doi: 10.1002/dev.22003.

Salcedo-Arellano MJ, Dufour B, McLennan Y, Martinez-Cerdeno V, Hagerman R. Fragile X syndrome and associated disorders: Clinical aspects and pathology.   Neurobiol Dis. 2020 Mar;136:104740. doi: 10.1016/j.nbd.2020.104740.

Salcedo-Arellano MJ, Cabal-Herrera AM, Tassanakijpanich N, McLennan YA, Hagerman RJ.  Ataxia as the Major Manifestation of Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS): Case Series.   Biomedicines. 2020 May 25;8(5):E136. doi: 10.3390/biomedicines8050136.

Salcedo-Arellano MJ, Cabal-Herrera AM, Punatar RH, Clark CJ, Romney CA, Hagerman RJ.  Overlapping Molecular Pathways Leading to Autism Spectrum Disorders, Fragile X Syndrome, and Targeted Treatments.  Neurotherapeutics. 2020 Nov 19. doi: 10.1007/s13311-020-00968-6.

Santos E, Emeka-Nwonovo C, Wang JY, Schneider A, Tassone F, Hagerman P, Hagerman R.  Developmental aspects of FXAND in a man with the FMR1 premutation.   Mol Genet Genomic Med. 2020 Feb;8(2):e1050. doi: 10.1002/mgg3.1050.

Scott H, Harvey DJ, Li Y, McLennan YA, Johnston CK, Shickman R, Piven J, Schweitzer JB, Hessl D.  Cognitive Training Deep Dive: The Impact of Child, Training Behavior and Environmental Factors within a Controlled Trial of Cogmed for Fragile X Syndrome.  Brain Sci. 2020 Sep 25;10(10):E671. doi: 10.3390/brainsci10100671.

Schmitt LM, Wang J, Pedapati EV, Thurman AJ, Abbeduto L, Erickson CA, Sweeney JA. A neurophysiological model of speech production deficits in fragile X syndrome.  Brain Commun. 2020;2(1):fcz042. doi: 10.1093/braincomms/fcz042.

Schmuck MR, Keil KP, Sethi S, Morgan RK, Lein PJ.  Automated high content image analysis of dendritic arborization in primary mouse hippocampal and rat cortical neurons in culture.  J Neurosci Methods. 2020 Jul 15;341:108793. doi: 10.1016/j.jneumeth.2020.108793.

Schneider A, Winarni TI, Cabal-Herrera AM, Bacalman S, Gane L, Hagerman P, Tassone F, Hagerman R. Elevated FMR1-mRNA and lowered FMRP - A double-hit mechanism for psychiatric features in men with FMR1 premutations.  Transl Psychiatry. 2020 Jun 23;10(1):205. doi: 10.1038/s41398-020-00863-w.

Schneider A, Summers S, Tassone F, Seritan A, Hessl D, Hagerman P, Hagerman R. Women with Fragile X-associated Tremor/Ataxia Syndrome.  Mov Disord Clin Pract. 2020 Sep 23;7(8):910-919. doi: 10.1002/mdc3.13084.

Shaffer RC, Schmitt L, John Thurman A, Abbeduto L, Hong M, Pedapati E, Dominick K, Sweeney J, Erickson C. The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development.   Brain Sci. 2020 Jan 26;10(2). pii: E66. doi: 10.3390/brainsci10020066.

Shin HM, Bennett DH, Calafat AM, Tancredi D, Hertz-Picciotto I. Modeled prenatal exposure to per- and polyfluoroalkyl substances in association with child autism spectrum disorder: A case-control study.  Environ Res. 2020 Jul;186:109514. doi: 10.1016/j.envres.2020.109514.

Silverman JL, Nithianantharajah J, Der-Avakian A, Young JW, Sukoff Rizzo SJ. Lost in translation: At the crossroads of face validity and translational utility of behavioral assays in animal models for the development of therapeutics. Neurosci Biobehav Rev. 2020 Jul 15;116:452-453. doi: 10.1016/j.neubiorev.2020.07.008.

Solomon M, Gordon A, Iosif AM, Geddert R, Krug MK, Mundy P, Hessl D. Using the NIH Toolbox to Assess Cognition in Adolescents and Young Adults with Autism Spectrum Disorders. Autism Res. 2020 Oct 2. doi: 10.1002/aur.2399.

Sotelo-Orozco J, Abbeduto L, Hertz-Picciotto I, Slupsky CM. Association Between Plasma Metabolites and Psychometric Scores Among Children With Developmental Disabilities: Investigating Sex-Differences. Front Psychiatry. 2020 Dec 22;11:579538. doi: 10.3389/fpsyt.2020.579538.

Supasai S, González EA, Rowland DJ, Hobson B, Bruun DA, Guignet MA, Soares S, Singh V, Wulff H, Saito N, Harvey DJ, Lein PJ. Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate. Eur J Pharmacol. 2020 Nov 5;886:173538. doi: 10.1016/j.ejphar.2020.173538.

Tassanakijpanich N, Cohen J, Cohen R, Srivatsa UN, Hagerman RJ. Cardiovascular Problems in the Fragile X Premutation. Front Genet. 2020 Oct 8;11:586910. doi: 10.3389/fgene.2020.586910.

Thurman AJ, Potter LA, Kim K, Tassone F, Banasik A, Potter SN, Bullard L, Nguyen V, McDuffie A, Hagerman R, Abbeduto L. Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome.   J Neurodev Disord. 2020 Apr 22;12(1):12. doi: 10.1186/s11689-020-09315-4.

Vogel Ciernia A, Laufer BI, Hwang H, Dunaway KW, Mordaunt CE, Coulson RL, Yasui DH, LaSalle JM. Epigenomic Convergence of Neural-Immune Risk Factors in Neurodevelopmental Disorder Cortex.   Cereb Cortex. 2020 Mar 21;30(2):640-655. doi: 10.1093/cercor/bhz115.

Waizbard-Bartov E, Ferrer E, Young GS, Heath B, Rogers S, Wu Nordahl C, Solomon M, Amaral DG. Trajectories of Autism Symptom Severity Change During Early Childhood.   J Autism Dev Disord. 2020 May 14. doi: 10.1007/s10803-020-04526-z.

Wang JY, Danial M, Soleymanzadeh C, Kim B, Xia Y, Kim K, Tassone F, Hagerman RJ, Rivera SM. Cortical gyrification and its relationships with molecular measures and cognition in children with the FMR1 premutation.   Sci Rep. 2020 Sep 29;10(1):16059. doi: 10.1038/s41598-020-73040-0.

Zafarullah M, Tang HT, Durbin-Johnson B, Fourie E, Hessl D, Rivera SM, Tassone F. FMR1 locus isoforms: potential biomarker candidates in fragile X-associated tremor/ataxia syndrome (FXTAS).   Sci Rep. 2020 Jul 6;10(1):11099. doi: 10.1038/s41598-020-67946-y.

Zafarullah M, Palczewski G, Rivera SM, Hessl DR, Tassone F. Metabolic profiling reveals dysregulated lipid metabolism and potential biomarkers associated with the development and progression of Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS).   FASEB J. 2020 Dec;34(12):16676-16692. doi: 10.1096/fj.202001880R.

Zhu Y, Mordaunt CE, Durbin-Johnson BP, Caudill MA, Malysheva OV, Miller JW, Green R, James SJ, Melnyk SB, Fallin MD, Hertz-Picciotto I, Schmidt RJ, LaSalle JM. Expression Changes in Epigenetic Gene Pathways Associated With One-Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non-Typical Neurodevelopment.   Autism Res. 2020 Nov 7. doi: 10.1002/aur.2428.

2019

Barkoski JM, Busgang SA, Bixby M, Bennett D, Schmidt RJ, Barr DB, Panuwet P, Gennings C, Hertz-Picciotto I. Prenatal phenol and paraben exposures in relation to child neurodevelopment including autism spectrum disorders in the MARBLES study. »   Environ Res. 2019 Dec;179(Pt A):108719. doi: 10.1016/j.envres.2019.108719.

Biag HMB, Potter LA, Wilkins V, Afzal S, Rosvall A, Salcedo-Arellano MJ, Rajaratnam A, Manzano-Nunez R, Schneider A, Tassone F, Rivera SM, Hagerman RJ. Metformin treatment in young children with fragile X syndrome. » Mol Genet Genomic Med. 2019 Sep 14:e956. doi: 10.1002/mgg3.956.

Bolandparvaz A, Harriman R, Alvarez K, Lilova K, Zang Z, Lam A, Edmiston E, Navrotsky A, Vapniarsky N, Van De Water J, Lewis JS. Towards a nanoparticle-based prophylactic for maternal autoantibody-related autism. »  Nanomedicine. 2019 Oct;21:102067. doi: 10.1016/j.nano.2019.102067.

Bruce M, Streifel KM, Boosalis CA, Heuer L, González EA, Li S, Harvey DJ, Lein PJ, Van de Water J. Acute peripheral immune activation alters cytokine expression and glial activation in the early postnatal rat brain. » J Neuroinflammation. 2019 Oct 31;16(1):200. doi: 10.1186/s12974-019-1569-2.

Cameron LP, Benson CJ, DeFelice B, Fiehn O, Olson DE. Chronic, Intermittent Microdoses of the Psychedelic N,N-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents. » ACS Chem Neurosci. 2019 Jul 17;10(7):3261-3270. doi: 10.1021/acschemneuro.8b00692.

Copping NA, Adhikari A, Petkova SP, Silverman JL. Genetic backgrounds have unique seizure response profiles and behavioral outcomes following convulsant administration. » Epilepsy Behav. 2019 Dec;101(Pt A):106547. doi: 10.1016/j.yebeh.2019.106547.

De Meo-Monteil R, Nordahl CW, Amaral DG, Rogers SJ, Harootonian SK, Martin J, Rivera SM, Saron CD. Differential Altered Auditory Event-Related Potential Responses in Young Boys on the Autism Spectrum With and Without Disproportionate Megalencephaly. » Autism Res. 2019 Jun 3. doi: 10.1002/aur.2137.

Dutta R, Crawley JN. Behavioral Evaluation of Angelman Syndrome Mice at Older Ages. » Neuroscience. 2019 Nov 12:S0306-4522(19)30719-5. doi: 10.1016/j.neuroscience.2019.10.027.

Ezell J, Hogan A, Fairchild A, Hills K, Klusek J, Abbeduto L, Roberts J. Prevalence and Predictors of Anxiety Disorders in Adolescent and Adult Males with Autism Spectrum Disorder and Fragile X Syndrome. » J Autism Dev Disord. 2019 Mar;49(3):1131-1141. doi: 10.1007/s10803-018-3804-6.

Granillo L, Sethi S, Keil KP, Lin Y, Ozonoff S, Iosif AM, Puschner B, Schmidt RJ. Polychlorinated biphenyls influence on autism spectrum disorder risk in the MARBLES cohort. » Environ Res. 2019 Apr;171:177-184. doi: 10.1016/j.envres.2018.12.061.

Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Wahab A, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ. Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication. »  Neurobiol Dis. 2019 Mar 21. pii: S0969-9961(19)30073-7. doi: 10.1016/j.nbd.2019.03.019.

Hennebelle M, Morgan RK, Sethi S, Zhang Z, Chen H, Grodzki AC, Lein PJ, Taha AY. Linoleic acid-derived metabolites constitute the majority of oxylipins in the rat pup brain and stimulate axonal growth in primary rat cortical neuron-glia co-cultures in a sex-dependent manner. » J Neurochem. 2019 Jul 8. doi: 10.1111/jnc.14818.

Hessl D, Harvey D, Sansone S, Crestodina C, Chin J, Joshi R, Hagerman RJ, Berry-Kravis E. Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome. »  PLoS One. 2019 Jan 17;14(1):e0209984. doi: 10.1371/journal.pone.0209984.

Heuer LS Croen LA, Jones KL, Yoshida CK, Hansen RL, Yolken R, Zerbo O, DeLorenze G, Kharrazi M, Ashwood P, Van de Water J. Exploratory Examination of Neonatal Cytokines and Chemokines as Predictors of Autism Risk: The Early Markers for Autism Study. »   Biol Psychiatry. 2019 Aug 15;86(4):255-264. doi: 10.1016/j.biopsych.2019.04.037.

Kentner AC, Bilbo SD, Brown AS, Hsiao EY, McAllister A, Meyer U, Pearce BD, Pletnikov MV, Yolken RH, Bauman MD. Maternal immune activation: reporting guidelines to improve the rigor, reproducibility, and transparency of the model. »  Neuropsychopharmacology. 2019 Jan;44(2):245-258. doi: 10.1038/s41386-018-0185-7.

Klusek J, Moser C, Schmidt J, Abbeduto L, Roberts JE. A novel eye-tracking paradigm for indexing social avoidance-related behavior in fragile X syndrome. » Am J Med Genet B Neuropsychiatr Genet. 2019 Aug 16. doi: 10.1002/ajmg.b.32757.

Kover ST, Abbeduto L. Syntactic Ability of Girls With Fragile X Syndrome: Phonological Memory and Discourse Demands on Complex Sentence Use. » Am J Intellect Dev Disabil. 2019 Nov;124(6):511-534. doi: 10.1352/1944-7558-124.6.511.

Lauterborn JC, Schultz MN, Le AA, Amani M, Friedman AE, Leach PT, Gall CM1 Lynch GS, Crawley JN. Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities. » Transl Psychiatry. 2019 Jun 10;9(1):166. doi: 10.1038/s41398-019-0495-5.

Le Duc D, Giulivi C, Hiatt SM, Napoli E, Panoutsopoulos A, Harlan De Crescenzo A, Kotzaeridou U, Syrbe S, Anagnostou E, Azage M, Bend R, Begtrup A, Brown NJ, Büttner B, Cho MT, Cooper GM, Doering JH, Dubourg C, Everman DB, Hildebrand MS, Santos FJR, Kellam B, Keller-Ramey J, Lemke JR, Liu S, Niyazov D, Payne K, Person R, Quélin C, Schnur RE, Smith BT, Strober J, Walker S, Wallis M, Walsh L, Yang S, Yuen RKC, Ziegler A, Sticht H, Pride MC, Orosco L, Martínez-Cerdeño V, Silverman JL, Crawley JN, Scherer SW, Zarbalis KS, Jamra R. Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size. »  Brain. 2019 Sep 1;142(9):2617-2630. doi: 10.1093/brain/awz198.

Lee SC, Quinn TP, Lai J, Kong SW, Hertz-Picciotto I, Glatt SJ, Crowley TM, Venkatesh S, Nguyen T. Solving for X: Evidence for sex-specific autism biomarkers across multiple transcriptomic studies. » Am J Med Genet B Neuropsychiatr Genet. 2019 Sep;180(6):377-389. doi: 10.1002/ajmg.b.32701.

Lopez SJ, Laufer BI, Beitnere U, Berg EL, Silverman JL, O'Geen H, Segal DJ, LaSalle JM. Imprinting effects of UBE3A loss on synaptic gene networks and Wnt signaling pathways. »  Hum Mol Genet. 2019 Nov 15;28(22):3842-3852. doi: 10.1093/hmg/ddz221.

McCabe KL, Popa AM, Durdle C, Amato M, Cabaral MH, Cruz J, Wong LM, Harvey D, Tartaglia N, Simon TJ. Quantifying the resolution of spatial and temporal representation in children with 22q11.2 deletion syndrome. » J Neurodev Disord. 2019 Dec 20;11(1):40. doi: 10.1186/s11689-019-9301-1.

Miller M, Iosif AM, Young GS, Bell LJ, Schwichtenberg AJ, Hutman T, Ozonoff S. The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder. » J Child Psychol Psychiatry. 2019 May;60(5):516-523. doi: 10.1111/jcpp.13003.

Noctor SC, Penna E, Shepherd H, Chelson C, Barger N, Martínez-Cerdeño V, Tarantal AF. Periventricular microglial cells interact with dividing precursor cells in the nonhuman primate and rodent prenatal cerebral cortex. » J Comp Neurol. 2019 Jul 1;527(10):1598-1609. doi: 10.1002/cne.24604.

Orozco JS, Hertz-Picciotto I, Abbeduto L, Slupsky CM. Metabolomics analysis of children with autism, idiopathic-developmental delays, and Down syndrome. » Transl Psychiatry. 2019 Oct 3;9(1):243. doi: 10.1038/s41398-019-0578-3.

Proskocil BJ, Grodzki ACG, Jacoby DB, Lein PJ, Fryer AD. Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells. »  Am J Respir Cell Mol Biol. 2019 Nov;61(5):620-630. doi: 10.1165/rcmb.2018-0257OC.

Protic D, Aydin EY, Tassone F, Tan MM, Hagerman RJ, Schneider A. Cognitive and behavioral improvement in adults with fragile X syndrome treated with metformin-two cases. » Mol Genet Genomic Med. 2019 May 18:e745. doi: 10.1002/mgg3.745.

Rhine MA, Parrott JM, Schultz MN, Kazdoba TM, Crawley JN. Hypothesis-driven investigations of diverse pharmacological targets in two mouse models of autism. » Autism Res. 2019 Jan 17. doi: 10.1002/aur.2066.

Rose D, Ashwood P. Rapid Communication: Plasma Interleukin-35 in Children with Autism. » Brain Sci. 2019 Jun 27;9(7). pii: E152. doi: 10.3390/brainsci9070152.

Ryan AM, Freeman SM, Murai T, Lau AR, Palumbo MC, Hogrefe CE, Bales KL, Bauman MD. Non-invasive Eye Tracking Methods for New World and Old World Monkeys. » Front Behav Neurosci. 2019 Mar 5;13:39. doi: 10.3389/fnbeh.2019.00039.

Ryan AM, Berman RF, Bauman MD. Bridging the species gap in translational research for neurodevelopmental disorders. » Neurobiol Learn Mem. 2019 Nov;165:106950. doi: 10.1016/j.nlm.2018.10.006.

Sanctuary MR, Kain JN, Chen SY, Kalanetra K, Lemay DG, Rose DR, Yang HT, Tancredi DJ, German JB, Slupsky CM, Ashwood P, Mills DA, Smilowitz JT, Angkustsiri K. Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms. »  PLoS One. 2019 Jan 9;14(1):e0210064. doi: 10.1371/journal.pone.0210064.

Solomon M, Iosif AM, Krug MK, Nordahl CW, Adler E, Mirandola C, Ghetti S. Emotional false memory in autism spectrum disorder: More than spared. »   J Abnorm Psychol. 2019 May;128(4):352-363. doi: 10.1037/abn0000418.

Stamou M, Lein PJ. Fc Gamma Receptors are Expressed in the Developing Rat Brain and Activate Downstream Signaling Molecules upon Cross-Linking with Immune Complex. » J Neurol Neuromedicine. 2019;4(1):26-29. doi: 10.29245/2572.942X/2019/1.1243.

Stahmer AC, Vejnoska S, Iadarola S, Straiton D, Segovia FR, Luelmo P, Morgan EH, Lee HS, Javed A, Bronstein B, Hochheimer S, Cho E, Aranbarri A, Mandell D, Hassrick EM, Smith T, Kasari C. Caregiver Voices: Cross-Cultural Input on Improving Access to Autism Services. » J Racial Ethn Health Disparities. 2019 Aug;6(4):752-773. doi: 10.1007/s40615-019-00575-y.

Stahmer A, Brookman-Frazee L. Utilizing Community-Based Implementation Trials to Advance Understanding of Service Disparities in Autism Spectrum Disorder. »  Glob Pediatr Health. 2019 Jun 13;6:2333794X19854939. doi: 10.1177/2333794X19854939.

Stahmer AC, Dababnah S, Rieth SR. Considerations in implementing evidence-based early autism spectrum disorder interventions in community settings. » Pediatr Med. 2019 May;2. pii: 18. doi: 10.21037/pm.2019.05.01.

Talbott MR, Dufek S, Zwaigenbaum L, Bryson S, Brian J, Smith IM, Rogers SJ. Brief Report: Preliminary Feasibility of the TEDI: A Novel Parent-Administered Telehealth Assessment for Autism Spectrum Disorder Symptoms in the First Year of Life. » J Autism Dev Disord. 2019 Nov 27. doi: 10.1007/s10803-019-04314-4.

Tan MM, Dy JB, Salcedo-Arellano MJ, Tassone F, Hagerman RJ. Fragile X- associated Neuropsychiatric Disorders: A Case Report. »  Future Neurol. 2019 May;14(2). doi: 10.2217/fnl-2018-0040.

Thurman AJ, Hoyos Alvarez C. Language Performance in Preschool-Aged Boys with Nonsyndromic Autism Spectrum Disorder or Fragile X Syndrome. » J Autism Dev Disord. 2019 Feb 19. doi:10.1007/s10803-019-03919-z.

Villalón-Reina JE, Martínez K, Qu X, Ching CRK, Nir TM, Kothapalli D, Corbin C, Sun D, Lin A, Forsyth JK, Kushan L, Vajdi A, Jalbrzikowski M, Hansen L, Jonas RK, van Amelsvoort T, Bakker G, Kates WR, Antshel KM, Fremont W, Campbell LE, McCabe KL Daly E, Gudbrandsen M, Murphy CM, Murphy D, Craig M, Emanuel B, McDonald-McGinn DM, Vorstman JAS, Fiksinski AM, Koops S, Ruparel K, Roalf D, Gur RE, Eric Schmitt J, Simon TJ, Goodrich-Hunsaker NJ, Durdle C, Doherty JL, Cunningham AC, van den Bree M, Linden DEJ, Owen M, Moss H, Kelly S, Donohoe G, Murphy KC, Arango C, Jahanshad N, Thompson PM, Bearden CE. Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study. » Mol Psychiatry. 2019 Jul 29. doi: 10.1038/s41380-019-0450-0.

Wang JY, Hessl D, Tassone F, Kim K, Hagerman RJ, Rivera SM. Interaction between ventricular expansion and structural changes in the corpus callosum and putamen in males with FMR1 normal and premutation alleles. »  Neurobiol Aging. 2019 Sep 24. pii: S0197-4580(19)30330-6. doi: 10.1016/j.neurobiolaging.2019.09.009.

Young G, Constantino JN, Dvorak S, Belding A, Gangi D, Hill A, Hill M, Miller M, Parikh C, Schwichtenberg AJ, Solis E, Ozonoff S. A video-based measure to identify autism risk in infancy. » J Child Psychol Psychiatry. 2019 Aug 1. doi: 10.1111/jcpp.13105.

Zhu Y, Mordaunt CE, Yasui DH, Marathe R, Coulson RL, Dunaway KW, Jianu JM, Walker CK, Ozonoff S, Hertz-Picciotto I, Schmidt RJ, LaSalle JM. Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study. »  Hum Mol Genet. 2019 Aug 15;28(16):2659-2674. doi: 10.1093/hmg/ddz084.

2018

Abbeduto L, Thurman AJ, McDuffie A, Klusek J, Feigles RT, Ted Brown W, Harvey DJ, Adayev T, LaFauci G, Dobkins C, Roberts JE. ASD Comorbidity in Fragile X Syndrome: Symptom Profile and Predictors of Symptom Severity in Adolescent and Young Adult Males. » J Autism Dev Disord. 2018 Oct 31. doi: 10.1007/s10803-018-3796-2.

Adhikari A, Copping NA, Onaga B, Pride MC, Coulson RL, Yang M, Yasui DH, LaSalle JM, Silverman JL. Cognitive deficits in the Snord116 deletion mouse model for Prader-Willi syndrome. » Neurobiol Learn Mem. 2018 May 23. pii: S1074-7427(18)30119-9. doi: 10.1016/j.nlm.2018.05.011.

Adlof SM, Klusek J, Hoffmann A, Chitwood KL, Brazendale A, Riley K, Abbeduto LJ, Roberts JE. Reading in Children With Fragile X Syndrome: Phonological Awareness and Feasibility of Intervention. »   Am J Intellect Dev Disabil. 2018 May;123(3):193-211. doi: 10.1352/1944-7558-123.3.193.

Ashwood P. Differential T Cell Levels of Tumor Necrosis Factor Receptor-II in Children With Autism. » Front Psychiatry. 2018 Nov 20;9:543. doi: 10.3389/fpsyt.2018.00543.

Ariza J, Rogers H, Hashemi E, Noctor SC, Martínez-Cerdeño V. The Number of Chandelier and Basket Cells Are Differentially Decreased in Prefrontal Cortex in Autism. » Cereb Cortex. 2018 Feb 1;28(2):411-420. doi: 10.1093/cercor/bhw349.

Avino TA, Barger N, Vargas MV, Carlson EL, Amaral DG, Bauman MD, Schumann CM. Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism. » Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3710-3715. doi: 10.1073/pnas.1801912115.

Barkoski J, Bennett D, Tancredi D, Barr DB, Elms W, Hertz-Picciotto I. Variability of urinary pesticide metabolite concentrations during pregnancy in the MARBLES Study. » Environ Res. 2018 Aug;165:400-409. doi: 10.1016/j.envres.2018.05.002.

Bauman MD, Schumann CM. Advances in nonhuman primate models of autism: Integrating neuroscience and behavior. » Exp Neurol. 2018 Jan;299(Pt A):252-265. doi: 10.1016/j.expneurol.2017.07.021.

Bauman MD, Schumann CM, Carlson EL, Taylor SL, Vázquez-Rosa E, Cintrón-Pérez CJ, Shin MK, Williams NS, Pieper AA. Neuroprotective efficacy of P7C3 compounds in primate hippocampus. » Transl Pychiatry 2018 Sep 26;8(1):202. doi: 10.1038/s41398-018-0244-1.

Berg EL, Copping NA, Rivera JK, Pride MC, Careaga M, Bauman MD, Berman RF, Lein PJ, Harony-Nicolas H, Buxbaum JD, Ellegood J, Lerch JP, Wöhr M, Silverman JL. Developmental social communication deficits in the Shank3 rat model of phelan-mcdermid syndrome and autism spectrum disorder. » Autism Res. 2018 Jan 29. doi: 10.1002/aur.1925.

Calvin Ly, Alexandra C. Greb, Lindsay P. Cameron, Jonathan M. Wong, Eden V. Barragan, Paige C. Wilson, Kyle F. Burbach, Sina Soltanzadeh Zarandi, Alexander Sood, Michael R. Paddy, Whitney C. Duim, Megan Y. Dennis, A. Kimberley McAllister, Kassandra M. Ori-McKenney, John A. Gray, David E. Olson. Psychedelics Promote Structural and Functional Neural Plasticity. » CelRep.2018.05.022 Pages 3170-3182.

Cameron LP, Benson CJ, Dunlap LE, Olson DE. Effects of N, N-Dimethyltryptamine on Rat Behaviors Relevant to Anxiety and Depression. »   ACS Chem Neurosci. 2018 Jul 18;9(7):1582-1590. doi: 10.1021/acschemneuro.8b00134..

Careaga M, Taylor SL, Chang C, Chiang A, Ku KM, Berman RF, Van de Water JA, Bauman MD. Variability in PolyIC induced immune response: Implications for preclinical maternal immune activation models. » J Neuroimmunol. 2018 Oct 15;323:87-93. doi: 10.1016/j.jneuroim.2018.06.014.

Castañeda AR, Pinkerton KE, Bein KJ, Magaña-Méndez A, Yang HT, Ashwood P, Vogel CFA. Ambient particulate matter activates the aryl hydrocarbon receptor in dendritic cells and enhances Th17 polarization. » Toxicol Lett. 2018 Aug;292:85-96. doi: 10.1016/j.toxlet.2018.04.020.

Chen CY, Di Lucente J, Lin YC, Lien CC, Rogawski MA, Maezawa I, Jin LW. Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome. » Neurobiol Dis. 2018 Jan;109 (Pt A):25-32. doi: 10.1016/j.nbd.2017.09.006.

Cohen SCL, Harvey DJ, Shields RH, Shields GS, Rashedi RN, Tancredi DJ, Angkustsiri K, Hansen RL, Schweitzer JB. Effects of Yoga on Attention, Impulsivity, and Hyperactivity in Preschool-Aged Children with Attention-Deficit Hyperactivity Disorder Symptoms. » J Dev Behav Pediatr. 2018 Mar 13. doi: 10.1097/DBP.0000000000000552.

Conners FA, Tungate AS, Abbeduto L, Merrill EC, Faught GG. Growth and Decline in Language and Phonological Memory Over Two Years Among Adolescents With Down Syndrome. »   Am J Intellect Dev Disabil. 2018 Mar;123(2):103-118. doi: 10.1352/1944-7558-123.2.103.

Coulson RL, Powell WT, Yasui DH, Dileep G, Resnick J, LaSalle JM. Prader-Willi locus Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN. » Hum Mol Genet. 2018 Dec 1;27(23):4051-4060. doi: 10.1093/hmg/ddy296.

Coulson RL, Yasui DH, Dunaway KW, Laufer BI, Vogel Ciernia A, Zhu Y, Mordaunt CE, Totah TS, LaSalle JM. Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex. » Nat Commun. 2018 Apr 24;9(1):1616. doi: 10.1038/s41467-018-03676-0.

Del Hoyo Soriano L, Thurman AJ, Harvey DJ, Ted Brown W, Abbeduto L. Genetic and maternal predictors of cognitive and behavioral trajectories in females with fragile X syndrome.  » J Neurodev Disord. 2018 Jun 20;10(1):22. doi: 10.1186/s11689-018-9240-2.

Del Hoyo Soriano L, Thurman AJ, Abbeduto L. Specificity: A Phenotypic Comparison of Communication-Relevant Domains Between Youth With Down Syndrome and Fragile X Syndrome. »   Front Genet. 2018 Oct 1;9:424. doi: 10.3389/fgene.2018.00424.

Dy ABC, Tassone F, Eldeeb M, Salcedo-Arellano MJ, Tartaglia N, Hagerman R. Metformin as targeted treatment in fragile X syndrome. » Clin Genet. 2018 Feb;93(2):216-222. doi: 10.1111/cge.13039.

El-Deeb M, Adams P, Schneider A, Salcedo-Arellano MJ, Tassone F, Hagerman R. Fentanyl overdose in a female with the FMR1 premutation and FXTAS. »   J Mol Genet (Isleworth). 2018 Nov;1(1). pii: 101. doi: 10.31038/JMG.1000101.

Ezell J, Hogan A, Fairchild A, Hills K, Klusek J, Abbeduto L, Roberts J. Prevalence and Predictors of Anxiety Disorders in Adolescent and Adult Males with Autism Spectrum Disorder and Fragile X Syndrome. » J Autism Dev Disord. 2018 Nov 14. doi: 10.1007/s10803-018-3804-6.

Granillo L, Sethi S, Keil KP, Lin Y, Ozonoff S, Iosif AM, Puschner B, Schmidt RJ. Polychlorinated biphenyls influence on autism spectrum disorder risk in the MARBLES cohort. »   Environ Res. 2018 Dec 25;171:177-184. doi: 10.1016/j.envres.2018.12.061.

Goodrich AJ, Volk HE, Tancredi DJ, McConnell R, Lurmann FW, Hansen RL, Schmidt RJ. Joint effects of prenatal air pollutant exposure and maternal folic acid supplementation on risk of autism spectrum disorder. »   Autism Res. 2018 Jan;11(1):69-80. doi: 10.1002/aur.1885.

Gulinello M, Mitchell HA, Chang Q, Timothy O'Brien W, Zhou Z, Abel T, Wang L, Corbin JG, Veeraragavan S, Samaco RC, Andrews NA, Fagiolini M, Cole TB, Burbacher TM, Crawley JN. Rigor and reproducibility in rodent behavioral research. »   Neurobiol Learn Mem. 2018 Jan 4. pii: S1074-7427(18)30001-7. doi: 10.1016/j.nlm.2018.01.001.

Hart LA, Thigpen AP, Willits NH, Lyons LA, Hertz-Picciotto I, Hart BL. Affectionate Interactions of Cats with Children Having Autism Spectrum Disorder. »   Front Vet Sci. 2018 Mar 12;5:39. doi: 10.3389/fvets.2018.00039.

Hashemi E, Ariza J, Rogers H, Noctor SC, Martínez-Cerdeño V. The Number of Parvalbumin-Expressing Interneurons Is Decreased in the Prefrontal Cortex in Autism. »   Cereb Cortex. 2018 Feb 1;28(2):690. doi: 10.1093/cercor/bhx063.

Hertz-Picciotto I, Schmidt RJ, Krakowiak P. Understanding environmental contributions to autism: Causal concepts and the state of science. »   Autism Res. 2018 Mar 23. doi: 10.1002/aur.1938.

Hertz-Picciotto I, Schmidt RJ, Walker CK, Bennett DH, Oliver M, Shedd-Wise KM, LaSalle JM, Giulivi C, Puschner B, Thomas J, Roa DL, Pessah IN, Van de Water J, Tancredi DJ, Ozonoff S. A Prospective Study of Environmental Exposures and Early Biomarkers in Autism Spectrum Disorder: Design, Protocols, and Preliminary Data from the MARBLES Study. »   Environ Health Perspect. 2018 Nov;126(11):117004. doi: 10.1289/EHP535.

Hughes HK, Ashwood P. Anti-Candida albicans IgG Antibodies in Children With Autism Spectrum Disorders. » Front Psychiatry. 2018 Nov 26;9:627. doi: 10.3389/fpsyt.2018.00627.

Hughes HK, Rose D, Ashwood P. The Gut Microbiota and Dysbiosis in Autism Spectrum Disorders. » Curr Neurol Neurosci Rep. 2018 Sep 24;18(11):81. doi: 10.1007/s11910-018-0887-6.

Jones KL, Pride MC, Edmiston E, Yang M, Silverman JL, Crawley JN, Van de Water J. Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism. » Mol Psychiatry. 2018 Jun 28. doi: 10.1038/s41380-018-0126-1.

Jones KL, Van de Water J. Maternal autoantibody related autism: mechanisms and pathways. »   Mol Psychiatry. 2018 Jun 22. doi: 10.1038/s41380-018-0099-0.

Keil KP, Miller GW, Chen H, Sethi S, Schmuck MR, Dhakal K, Kim JW, Lein PJ. PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. »   Arch Toxicol. 2018 Aug 21. doi: 10.1007/s00204-018-2285-x.

Keil KP, Sethi S, Wilson MD, Silverman JL, Pessah IN, Lein PJ. Genetic mutations in Ca2+ signaling alter dendrite morphology and social approach in juvenile mice. »   Genes Brain Behav. 2018 Oct 12:e12526. doi: 10.1111/gbb.12526.

Kerin T, Volk H, Li W, Lurmann F, Eckel S, McConnell R, Hertz-Picciotto I. Association Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder. »   J Autism Dev Disord. 2018 Jan;48(1):137-150. doi: 10.1007/s10803-017-3304-0.

Klusek J, Fairchild AJ, Roberts JE. Vagal Tone as a Putative Mechanism for Pragmatic Competence: An Investigation of Carriers of the FMR1 Premutation. »   J Autism Dev Disord. 2018 Aug 10. doi: 10.1007/s10803-018-3714-7.

Klusek J, Porter A, Abbeduto L, Adayev T, Tassone F, Mailick MR, Glicksman A, Tonnsen BL, Roberts JE. Curvilinear Association Between Language Disfluency and FMR1 CGG Repeat Size Across the Normal, Intermediate, and Premutation Range. »   Front Genet. 2018 Aug 24;9:344. doi: 10.3389/fgene.2018.00344.

Ligsay A, El-Deeb M, Salcedo-Arellano MJ, Schloemerkemper N, Grayson JS, Hagerman R. General Anesthetic Use in Fragile X Spectrum Disorders. »   J Neurosurg Anesthesiol. 2018 May 4. doi: 10.1097/ANA.0000000000000508.

Loveall SJ, Channell MM, Abbeduto L, Conners FA. Verb production by individuals with Down syndrome during narration. »   Res Dev Disabil. 2018 Nov 27;85:82-91. doi: 10.1016/j.ridd.2018.11.007.

Ly C, Greb AC, Cameron LP, Wong JM, Barragan EV, Wilson PC, Burbach KF, Soltanzadeh Zarandi S, Sood A, Paddy MR, Duim WC, Dennis MY, McAllister AK, Ori-McKenney KM, Gray JA, Olson DE. Psychedelics Promote Structural and Functional Neural Plasticity. »   Cell Rep. 2018 Jun 12;23(11):3170-3182. doi: 10.1016/j.celrep.2018.05.022.

Maezawa I, Nguyen HM, Di Lucente J, Jenkins DP, Singh V, Hilt S, Kim K, Rangaraju S, Levey AI, Wulff H, Jin LW. Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept. » Brain. 2018 Feb 1;141(2):596-612. doi: 10.1093/brain/awx346.

Martínez-Cerdeño V, Camacho J, Ariza J, Rogers H, Horton-Sparks K, Kreutz A, Behringer R, Rasweiler JJ 4th, Noctor SC. The Bat as a New Model of Cortical Development. »   Cereb Cortex. 2018 Nov 1;28(11):3880-3893. doi: 10.1093/cercor/bhx251.

Matt L, Kirk LM, Chenaux G, Speca DJ, Puhger KR, Pride MC, Qneibi M, Haham T, Plambeck KE, Stern-Bach Y, Silverman JL, Crawley JN, Hell JW, Díaz E. SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function. »   Cell Rep. 2018 Feb 27;22(9):2246-2253. doi: 10.1016/j.celrep.2018.02.026.

Miller M, Iosif AM, Young GS, Bell LJ, Schwichtenberg AJ, Hutman T, Ozonoff S. The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder. »   J Child Psychol Psychiatry. 2018 Dec 1. doi: 10.1111/jcpp.13003.

Napoli E, Schneider A, Wang JY, Trivedi A, Carrillo NR, Tassone F, Rogawski M, Hagerman RJ, Giulivi C. Allopregnanolone Treatment Improves Plasma Metabolomic Profile Associated with GABA Metabolism in Fragile X-Associated Tremor/Ataxia Syndrome: a Pilot Study. »   Mol Neurobiol. 2018 Sep 5. doi: 10.1007/s12035-018-1330-3.

Nelson S, McDuffie A, Banasik A, Tempero Feigles R, Thurman AJ, Abbeduto L. Inferential language use by school-aged boys with fragile X syndrome: Effects of a parent-implemented spoken language intervention. »   J Commun Disord. 2018 Feb 15;72:64-76. doi: 10.1016/j.jcomdis.2018.02.007.

Noctor SC, Penna E, Shepherd H, Chelson C, Barger N, Martínez-Cerdeño V, Tarantal AF. Periventricular microglial cells interact with dividing precursor cells in the nonhuman primate and rodent prenatal cerebral cortex. »   J Comp Neurol. 2018 Dec 15. doi: 10.1002/cne.24604.

Olson DE. Psychoplastogens: A Promising Class of Plasticity-Promoting Neurotherapeutics. »   J Exp Neurosci. 2018 Sep 19;12:1179069518800508. doi: 10.1177/1179069518800508.

Ozonoff S, Gangi D, Hanzel EP, Hill A, Hill MM, Miller M, Schwichtenberg AJ, Steinfeld MB, Parikh C, Iosif AM. Onset patterns in autism: Variation across informants, methods, and timing. »  Autism Res. 2018 May;11(5):788-797. doi: 10.1002/aur.1943.

Rieth SR, Haine-Schlagel R, Burgeson M, Searcy K, Dickson KS, Stahmer AC. Integrating a Parent-Implemented Blend of Developmental and Behavioral Intervention Strategies into Speech-Language Treatment for Toddlers at Risk for Autism Spectrum Disorder. »   Semin Speech Lang. 2018 Apr;39(2):114-124. doi: 10.1055/s-0038-1627483.

Roberts JE, Ezell JE, Fairchild AJ, Klusek J, Thurman AJ, McDuffie A, Abbeduto L. Biobehavioral composite of social aspects of anxiety in young adults with fragile X syndrome contrasted to autism spectrum disorder. »   Am J Med Genet B Neuropsychiatr Genet. 2018 Oct 11. doi: 10.1002/ajmg.b.32674.

Rose DR, Yang H, Serena G, Sturgeon C, Ma B, Careaga M, Hughes HK, Angkustsiri K, Rose M, Hertz-Picciotto I, Van de Water J, Hansen RL, Ravel J, Fasano A, Ashwood P. Differential immune responses and microbiota profiles in children with autism spectrum disorders and co-morbid gastrointestinal symptoms. »   Brain Behav Immun. 2018 Mar 20. pii: S0889-1591(18)30078-3. doi: 10.1016/j.bbi.2018.03.025.

Ryan AM, Berman RF, Bauman MD. Bridging the species gap in translational research for neurodevelopmental disorders. »   Neurobiol Learn Mem. 2018 Oct 19. pii: S1074-7427(18)30240-5. doi: 10.1016/j.nlm.2018.10.006.

Shaffo FC, Grodzki AC, Schelegle ES, Lein PJ. The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats. »   Toxicol Sci. 2018 Sep 1;165(1):244-253. doi: 10.1093/toxsci/kfy158.

Saldarriaga W, Salcedo-Arellano MJ, Rodriguez-Guerrero T, Ríos M, Fandiño-Losada A, Ramirez-Cheyne J, Lein PJ, Tassone F, Hagerman RJ. Increased severity of fragile X spectrum disorders in the agricultural community of Ricaurte, Colombia. »   Int J Dev Neurosci. 2018 Oct 29;72:1-5. doi: 10.1016/j.ijdevneu.2018.10.002.

Sethi S, Keil KP, Lein PJ. 3,3'-Dichlorobiphenyl (PCB 11) promotes dendritic arborization in primary rat cortical neurons via a CREB-dependent mechanism. »  Arch Toxicol. 2018 Sep 17. doi: 10.1007/s00204-018-2307-8.

Shelton AL, Wang JY, Fourie E, Tassone F, Chen A, Frizzi L, Hagerman RJ, Ferrer E, Hessl D, Rivera SM. Middle Cerebellar Peduncle Width-A Novel MRI Biomarker for FXTAS? »    Front Neurosci. 2018 Jun 25;12:379. doi: 10.3389/fnins.2018.00379.

Shen MD, Nordahl CW, Li DD, Lee A, Angkustsiri K, Emerson RW, Rogers SJ, Ozonoff S, Amaral DG. Extra-axial cerebrospinal fluid in high-risk and normal-risk children with autism aged 2-4 years: a case-control study. » Lancet Psychiatry. 2018 Nov;5(11):895-904. doi: 10.1016/S2215-0366(18)30294-3.

Shickman R, Famula J, Tassone F, Leehey M, Ferrer E, Rivera SM, Hessl D. Age- and CGG Repeat-Related Slowing of Manual Movement in Fragile X Carriers: A Prodrome of Fragile X-Associated Tremor Ataxia Syndrome?  »   Mov Disord. 2018 Feb 1. doi: 10.1002/mds.27314.

Shin HM, Schmidt RJ, Tancredi D, Barkoski J, Ozonoff S, Bennett DH, Hertz-Picciotto I. Prenatal exposure to phthalates and autism spectrum disorder in the MARBLES study. »   Environ Health. 2018 Dec 5;17(1):85. doi: 10.1186/s12940-018-0428-4.

Silverman JL, Ellegood J. Behavioral and neuroanatomical approaches in models of neurodevelopmental disorders: opportunities for translation. »   Curr Opin Neurol. 2018 Apr;31(2):126-133. doi: 10.1097/WCO.0000000000000537.

Solomon M, Iosif AM, Reinhardt VP, Libero LE, Nordahl CW, Ozonoff S, Rogers SJ, Amaral DG. What will my child's future hold? phenotypes of intellectual development in 2-8-year-olds with autism spectrum disorder. » Autism Res. 2018 Jan;11(1):121-132. doi: 10.1002/aur.1884.

Sowell KD, Uriu-Adams JY, Van de Water J, Chambers CD, Coles CD, Kable JA, Yevtushok L, Zymak-Zakutnya N, Wertelecki W, Keen CL; Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD). Implications of altered maternal cytokine concentrations on infant outcomes in children with prenatal alcohol exposure. » Alcohol. 2018 May;68:49-58. doi: 10.1016/j.alcohol.2017.08.006.

Stahmer AC, Suhrheinrich J, Schetter PL, McGhee Hassrick E. Exploring multi-level system factors facilitating educator training and implementation of evidence-based practices (EBP): a study protocol. » Implement Sci. 2018 Jan 8;13(1):3. doi: 10.1186/s13012-017-0698-1.

Stamou M, Grodzki AC, van Oostrum M, Wollscheid B, Lein PJ. Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex. » J Neuroinflammation. 2018 Jan 6;15(1):7. doi: 10.1186/s12974-017-1050-z.

Stoppel LJ, Kazdoba TM, Schaffler MD, Preza AR, Heynen A, Crawley JN, Bear MF. R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice. » Neuropsychopharmacology. 2018 Feb;43(3):513-524. doi: 10.1038/npp.2017.236.

Vogel Ciernia A, Yasui DH, Pride MC, Durbin-Johnson B, Noronha AB, Chang A, Knotts TA, Rutkowsky JR, Ramsey JJ, Crawley JN, LaSalle JM. PMeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome. »   JHum Mol Genet. 2018 Dec 1;27(23):4077-4093. doi: 10.1093/hmg/ddy301.

Weir RK, Bauman MD, Jacobs B, Schumann CM. Protracted dendritic growth in the typically developing human amygdala and increased spine density in young ASD brains. »   J Comp Neurol. 2018 Feb 1;526(2):262-274. doi: 10.1002/cne.24332.

Zhan L, Jenkins LM, Zhang A, Conte G, Forbes A, Harvey D, Angkustsiri K, Goodrich-Hunsaker NJ, Durdle C, Lee A, Schumann C, Carmichael O, Kalish K, Leow AD, Simon TJ. Baseline connectome modular abnormalities in the childhood phase of a longitudinal study on individuals with chromosome 22q11.2 deletion syndrome. » Hum Brain Mapp. 2018 Jan;39(1):232-248. doi: 10.1002/hbm.23838.

2017

AlOlaby RR, Sweha SR, Silva M, Durbin-Johnson B, Yrigollen CM, Pretto D, Hagerman RJ, Tassone F. Molecular biomarkers predictive of sertraline treatment response in young children with fragile X syndrome. » Brain Dev. 2017 Feb 24. pii: S0387-7604(17)30012-8. doi: 10.1016/j.braindev.2017.01.012.

Ashby SA, Channell MM, Abbeduto L. Inferential language use by youth with Down syndrome during narration. » Res Dev Disabil. 2017 Oct 12;71:98-108. doi: 10.1016/j.ridd.2017.10.002.

Bullard L, McDuffie A, Abbeduto L. Distance delivery of a parent-implemented language intervention for young boys with fragile X syndrome. » Autism Dev Lang Impair. 2017 Jan-Dec;2. doi: 10.1177/2396941517728690.

Cao Z, Xu J, Hulsizer S, Cui Y, Dong Y, Pessah IN. Influence of tetramethylenedisulfotetramine on synchronous calcium oscillations at distinct developmental stages of hippocampal neuronal cultures. » Neurotoxicology. 2017 Jan;58:11-22. doi: 10.1016/j.neuro.2016.10.015.

Careaga M, Murai T, Bauman MD. Maternal Immune Activation and Autism Spectrum Disorder: From Rodents to Nonhuman and Human Primates. » Biol Psychiatry. 2017 Mar 1;81(5):391-401. doi: 10.1016/j.biopsych.2016.10.020.

Channell MM, Loveall SJ, Conners FA, Harvey DJ, Abbeduto L. Narrative Language Sampling in Typical Development: Implications for Clinical Trials. » Am J Speech Lang Pathol. 2017 Dec 7:1-13. doi: 10.1044/2017_AJSLP-17-0046.

Chen H, Streifel KM, Singh V, Yang D, Mangini L, Wulff H, Lein PJ. BDE-47 and BDE-49 Inhibit Axonal Growth in Primary Rat Hippocampal Neuron-Glia Co-Cultures via Ryanodine Receptor-Dependent Mechanisms. » Toxicol Sci. 2017 Jan 12 pii: kfw259. doi: 10.1093/toxsci/kfw259.

Copping NA, Christian SGB, Ritter DJ, Islam MS, Buscher N, Zolkowska D, Pride MC, Berg EL, LaSalle JM, Ellegood J, Lerch JP, Reiter LT, Silverman JL, Dindot SV. Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome. » Hum Mol Genet. 2017 Oct 15;26(20):3995-4010. doi: 10.1093/hmg/ddx289.

Dhamne SC, Silverman JL, Super CE, Lammers SHT, Hameed MQ, Modi ME, Copping NA, Pride MC, Smith DG, Rotenberg A, Crawley JN, Sahin M. Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism. » Mol Autism. 2017 Jun 15;8:26. doi: 10.1186/s13229-017-0142-z. eCollection 2017.

Edmiston E, Ashwood P, Van de Water J. Autoimmunity, Autoantibodies, and Autism Spectrum Disorder. » Biol Psychiatry. 2017 Mar 1;81(5):383-390. doi: 10.1016/j.biopsych.2016.08.031.

Edmiston E, Jones KL, Vu T, Ashwood P, Van de Water J. Identification of the antigenic epitopes of maternal autoantibodies in autism spectrum disorders. » Brain Behav Immun. 2017 Dec 28. pii: S0889-1591(17)30555-X. doi: 10.1016/j.bbi.2017.12.014.

Esbensen AJ, Hooper SR, Fidler D, Hartley SL, Edgin J, d'Ardhuy XL, Capone G, Conners FA, Mervis CB, Abbeduto L, Rafii M, Krinsky-McHale SJ, Urv T, Group OMW. Outcome Measures for Clinical Trials in Down Syndrome. » Am J Intellect Dev Disabil. 2017 May;122(3):247-281. doi: 10.1352/1944-7558-122.3.247.

Fassbender C, Muhkerjee P, Schweitzer J. Minimizing Noise in Pediatric Task-Based functional MRI; Adolescents with Developmental Disabilities and Typical Development. »

Gangi DN, Schwichtenberg AJ, Iosif AM, Young GS, Baguio F, Ozonoff S. Gaze to faces across interactive contexts in infants at heightened risk for autism. » Autism. 2017 Jul 1:1362361317704421. doi: 10.1177/1362361317704421.

Gompers AL, Su-Feher L, Ellegood J, Copping NA, Riyadh MA, Stradleigh TW, Pride MC, Schaffler MD, Wade AA, Catta-Preta R, Zdilar I, Louis S, Kaushik G, Mannion BJ, Plajzer-Frick I, Afzal V, Visel A, Pennacchio LA, Dickel DE, Lerch JP, Crawley JN, Zarbalis KS, Silverman JL, Nord AS. Germline Chd8 haploinsufficiency alters brain development in mouse. » Nat Neurosci. 2017 Aug;20(8):1062-1073. doi: 10.1038/nn.4592.

Hashemi E, Ariza J, Rogers H, Noctor SC, Martínez-Cerdeño V. The Number of Parvalbumin-Expressing Interneurons Is Decreased in the Medial Prefrontal Cortex in Autism. » Cereb Cortex. 2017 Mar 1;27(3):1931-1943. doi: 10.1093/cercor/bhw021.

Holland EB, Feng W, Zheng J, Dong Y, Li X, Lehmler HJ, Pessah IN. An Extended Structure-Activity Relationship of Nondioxin-Like PCBs Evaluates and Supports Modeling Predictions and Identifies Picomolar Potency of PCB 202 Towards Ryanodine Receptors. » Toxicol Sci. 2017 Jan;155(1):170-181. doi: 10.1093/toxsci/kfw189.

Jiraanont P, Sweha SR, AlOlaby RR, Silva M, Tang HT, Durbin-Johnson B, Schneider A, Espinal GM, Hagerman PJ, Rivera SM, Hessl D, Hagerman RJ, Chutabhakdikul N, Tassone F. Clinical and molecular correlates in fragile X premutation females. » eNeurologicalSci. 2017 Jun;7:49-56. doi: 10.1016/j.ensci.2017.04.003.

Keil KP, Sethi S, Wilson MD, Chen H, Lein PJ. In vivo and in vitro sex differences in the dendritic morphology of developing murine hippocampal and cortical neurons. » Sci Rep. 2017 Aug 16;7(1):8486. doi: 10.1038/s41598-017-08459-z.

Klusek J, Ruber A, Roberts JE. Impaired eye contact in the FMR1 premutation is not associated with social anxiety or the broad autism phenotype. » Clin Neuropsychol. 2017 Oct 3:1-16. doi: 10.1080/13854046.2017.1384063.

Klusek J, LaFauci G, Adayev T, Brown WT, Tassone F, Roberts JE. Reduced vagal tone in women with the FMR1 premutation is associated with FMR1 mRNA but not depression or anxiety. » J Neurodev Disord. 2017 May 2;9:16. doi: 10.1186/s11689-017-9197-6. eCollection 2017.

Klusek J, Schmidt J, Fairchild AJ, Porter A, Roberts JE. Altered sensitivity to social gaze in the FMR1 premutation and pragmatic language competence. » J Neurodev Disord. 2017 Aug 24;9(1):31. doi: 10.1186/s11689-017-9211-z.

Leach PT, Crawley JN. Touchscreen learning deficits in Ube3a, Ts65Dn and Mecp2 mouse models of neurodevelopmental disorders with intellectual disabilities. » Genes Brain Behav. 2017 Dec 20. doi: 10.1111/gbb.12452.

Lewis Cohen SC, Harvey DJ, Shields RH, Shields GS, Rashedi RN, Tancredi DJ, Angkustsiri K, Hansen RL, Schweitzer JB. The Effects of Yoga on Attention, Impulsivity and Hyperactivity in Pre-school Age Children with ADHD Symptoms. » The Journal of Developmental & Behavioral Pediatrics.

Ligsay A, Van Dijck A, Nguyen DV, Lozano R, Chen Y, Bickel ES, Hessl D, Schneider A, Angkustsiri K, Tassone F, Ceulemans B, Kooy RF, Hagerman RJ. A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome. » J Neurodev Disord. 2017 Aug 2;9(1):26. doi: 10.1186/s11689-017-9207-8.

Lyall K, Schweitzer JB, Schmidt RJ, Hertz-Picciotto I, Solomon M. Inattention and hyperactivity in association with autism spectrum disorders in the CHARGE study. » Res Autism Spectr Disord. 2017 Mar;35:1-12. doi: 10.1016/j.rasd.2016.11.011.

Matherly SM, Klusek J, Thurman AJ, McDuffie A, Abbeduto L, Roberts JE. Cortisol profiles differentiated in adolescents and young adult males with fragile X syndrome versus autism spectrum disorder. » Dev Psychobiol. 2017 Nov 24. doi: 10.1002/dev.21578.

McCauley JB, Zajic MC, Oswald TM, Swain-Lerro LE, McIntyre NC, Harris MA, Trzesniewski K, Mundy PC, Solomon M. Brief Report: Investigating Relations Between Self-Concept and Performance in Reading and Math for School-Aged Children and Adolescents with Autism Spectrum Disorder. » J Autism Dev Disord. 2017 Nov 22. doi: 10.1007/s10803-017-3403-y.

McDuffie A, Banasik A, Bullard L, Nelson S, Feigles RT, Hagerman R, Abbeduto L. Distance delivery of a spoken language intervention for school-aged and adolescent boys with fragile X syndrome. » Dev Neurorehabil. 2017 Sep 28:1-16. doi: 10.1080/17518423.2017.1369189.

Meltzer A, Van de Water J. The Role of the Immune System in Autism Spectrum Disorder. » Neuropsychopharmacology. 2017 Jan;42(1):284-298. doi: 10.1038/npp.2016.158.

Miller M, Iosif AM, Young GS, Hill MM, Ozonoff S. Early detection of ADHD: Insights from infant siblings of children with autism. » Journal of Clinical Child and Adolescent Psychology. doi:10.1080/15374416.2016.1220314.

Miller M, Iosif AM, Hill M, Young GS, Schwichtenberg AJ, Ozonoff S. Response to name in Infants developing autism spectrum disorder: A prospective study. » Journal of Pediatrics. doi:10.1016/j.jpeds.2016.12.071.

Mousavi Nik A, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. » Mol Pharmacol. 2017 Apr 20. pii: mol.117.108563. doi: 10.1124/mol.117.108563.

Naigles LR, Johnson R, Mastergeorge A, Ozonoff S, Rogers SJ, Amaral DG, Nordahl CW. Neural correlates of language variability in preschool-aged boys with autism spectrum disorder. » Autism Res. 2017 Mar 16. doi: 10.1002/aur.1756.

Nik AM, Pressly B, Singh V, Antrobus S, Hulsizer S, Rogawski MA, Wulff H, Pessah IN. Rapid Throughput Analysis of GABAA Receptor Subtype Modulators and Blockers Using DiSBAC1(3) Membrane Potential Red Dye. » Mol Pharmacol. 2017 Jul;92(1):88-99. doi: 10.1124/mol.117.108563.

Onore C, Yang H, Van de Water J, Ashwood P. Dynamic Akt/mTOR Signaling in Children with Autism Spectrum Disorder. » Front Pediatr. 2017 Mar 15;5:43. doi: 10.3389/fped.2017.00043.

Ozonoff S, Li D, Deprey L, Hanzel EP, Iosif AM. Reliability of parent recall of symptom onset and timing in autism spectrum disorder. » Autism. 2017 Sep 1:1362361317710798. doi: 10.1177/1362361317710798.

Robin G, López JR, Espinal GM, Hulsizer S, Hagerman PJ, Pessah IN. Calcium dysregulation and Cdk5-ATM pathway involved in a mouse model of Fragile X-associated tremor-ataxia syndrome. » Hum Mol Genet. 2017 Apr 21. doi: 10.1093/hmg/ddx148.

Rose DR, Careaga M, Van de Water J, McAllister K, Bauman MD, Ashwood P. Long-term altered immune responses following fetal priming in a non-human primate model of maternal immune activation. » Brain Behav Immun. 2017 Jul;63:60-70. doi: 10.1016/j.bbi.2016.11.020.

Schmidt RJ, Kogan V, Shelton JF, Delwiche L, Hansen RL, Ozonoff S, Ma CC, McCanlies EC, Bennett DH, Hertz-Picciotto I, Tancredi DJ, Volk HE. Combined Prenatal Pesticide Exposure and Folic Acid Intake in Relation to Autism Spectrum Disorder. » Environ Health Perspect. 2017 Sep 8;125(9):097007. doi: 10.1289/EHP604.

Schumann CM, Sharp FR, Ander BP, Stamova B. Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain. » Mol Autism. 2017 Feb 7;8:4. doi: 10.1186/s13229-017-0117-0.

Schwartzer JJ, Careaga M, Coburn MA, Rose DR, Hughes HK, Ashwood P. Behavioral impact of maternal allergic-asthma in two genetically distinct mouse strains. »  Brain Behav Immun. 2017 Jul;63:99-107. doi: 10.1016/j.bbi.2016.09.007.

Schweitzer JB, Solomon M, Miller M, Hertz-Picciotto I. Comorbid Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorders. » ADHD Report, 25 (7), 1-12. Guilford Press. November, 2017.

Sethi S, Keil KP, Lein PJ. Species and Sex Differences in the Morphogenic Response of Primary Rodent Neurons to 3,3'-Dichlorobiphenyl (PCB 11). » Toxics.  2017 Dec 23;6(1). pii: E4. doi: 10.3390/toxics6010004.

Sukoff Rizzo SJ, Crawley JN. Behavioral Phenotyping Assays for Genetic Mouse Models of Neurodevelopmental, Neurodegenerative, and Psychiatric Disorders. » Annu Rev Anim Biosci. 2017 Feb 8;5:371-389. doi: 10.1146/annurev-animal-022516-022754.

Taylor SL, Ruhaak LR, Weiss RH, Kelly K, Kim K. Multivariate two-part statistics for analysis of correlated mass spectrometry data from multiple biological specimens. » Bioinformatics. 2017 Jan 1;33(1):17-25. doi: 10.1093/bioinformatics/btw578.

Thurman AJ, Kover ST, Ted Brown W, Harvey DJ, Abbeduto L. Noncomprehension Signaling in Males and Females With Fragile X Syndrome. » J Speech Lang Hear Res. 2017 Jun 2:1-16. doi: 10.1044/2016_JSLHR-L-15-0358.

Thurman AJ, McDuffie A, Hagerman R, Josol CK, Abbeduto L. Language Skills of Males with Fragile X Syndrome or Nonsyndromic Autism Spectrum Disorder. » J Autism Dev Disord. 2017 Jan 10. doi: 10.1007/s10803-016-3003-2.

Tylee DS, Hess JL, Quinn TP, Barve R, Huang H, Zhang-James Y, Chang J, Stamova BS, Sharp FR, Hertz-Picciotto I, Faraone SV, Kong SW, Glatt SJ. Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined-samples mega-analysis. » Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):181-201. doi: 10.1002/ajmg.b.32511.

Vogel Ciernia A, Pride MC, Durbin-Johnson B, Noronha A, Chang A, Yasui DH, Crawley J, LaSalle JM. Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering. » Hum Mol Genet. 2017 May 15;26(10):1839-1854. doi: 10.1093/hmg/ddx087.

Vogel Ciernia A, Careaga M, LaSalle JM, Ashwood P. Microglia from offspring of dams with allergic asthma exhibit epigenomic alterations in genes dysregulated in autism. » Glia. 2017 Nov 14. doi: 10.1002/glia.23261.

Wang JY, Hessl D, Hagerman RJ, Simon TJ, Tassone F, Ferrer E, Rivera SM. Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation. » Neurobiol Aging. 2017 Mar 18;55:11-19. doi: 10.1016/j.neurobiolaging.2017.03.018.

Wang JY, Trivedi AM, Carrillo NR, Yang J, Schneider A, Giulivi C, Adams P1, Tassone F, Kim K, Rivera SM, Lubarr N, Wu CY, Irwin RW, Brinton RD, Olichney JM, Rogawski MA, Hagerman RJ. Open-Label Allopregnanolone Treatment of Men with Fragile X-Associated Tremor/Ataxia Syndrome. » Neurotherapeutics. 2017 Oct;14(4):1073-1083. doi: 10.1007/s13311-017-0555-6..

Wilson MD, Sethi S, Lein PJ, Keil KP. Valid statistical approaches for analyzing sholl data: Mixed effects versus simple linear models. » J Neurosci Methods. 2017 Jan 16;279:33-43. doi: 10.1016/j.jneumeth.2017.01.003.

Zhang R, Pessah IN. Divergent Mechanisms Leading to Signaling Dysfunction in Embryonic Muscle by Bisphenol A and Tetrabromobisphenol A. » Mol Pharmacol. 2017 Apr;91(4):428-436. doi: 10.1124/mol.116.107342.

2016

Copping NA, Berg EL, Foley GM, Schaffler MD, Onaga BL, Buscher N, Silverman JL, Yang M. Touchscreen learning deficits and normal social approach behavior in the Shank3B model of Phelan-McDermid Syndrome and autism.  Neuroscience. 2016 May 14. pii: S0306-4522(16)30165-8. doi:10.1016/j.neuroscience.2016.05.016.

Crawley JN, Heyer WD, LaSalle JM. Autism and Cancer Share Risk Genes, Pathways, and Drug Targets.  Trends Genet. 2016 Jan 29. pii: S0168-9525(16)00002-0. doi:10.1016/j.tig.2016.01.001.

Dunaway K, Goorha S, Matelski L, Urraca N, Lein PJ, Korf I, Reiter LT, LaSalle JM. Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns.    Stem Cells. 2016 Dec 29. doi: 10.1002/stem.2563.

Dunaway KW, Islam MS, Coulson RL, Lopez SJ, Vogel Ciernia A, Chu RG, Yasui DH, Pessah IN, Lott P, Mordaunt C1 Meguro-Horike M, Horike SI, Korf I, LaSalle JM. Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes.  Cell Rep. 2016 Dec 13;17(11):3035-3048. doi: 10.1016/j.celrep.2016.11.058.

Foote M, Arque G, Berman RF, Santos M. Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) Motor Dysfunction Modeled in Mice.  Cerebellum. 2016 Oct;15(5):611-22. doi: 10.1007/s12311-016-0797-6.

Giulivi C, Napoli E, Tassone F, Halmai J, Hagerman R. Plasma Biomarkers for Monitoring Brain Pathophysiology in FMR1 Premutation Carriers.   Front Mol Neurosci. 2016 Aug 12;9:71. doi: 10.3389/fnmol.2016.00071. eCollection 2016.

Gossett A, Sansone S, Schneider A, Johnston C, Hagerman R, Tassone F, Rivera SM, Seritan AL, Hessl D. Psychiatric disorders among women with the fragile X premutation without children affected by fragile X syndrome.  Am J Med Genet B Neuropsychiatr Genet. 2016 Dec;171(8):1139-1147. doi: 10.1002/ajmg.b.32496.

Greiss Hess L, Fitzpatrick SE, Nguyen DV, Chen Y, Gaul KN, Schneider A, Lemons Chitwood K, Eldeeb MA, Polussa J, Hessl D, Rivera S, Hagerman RJ. Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome.  TJ Dev Behav Pediatr. 2016 Aug 24.

Hartanto TA, Krafft CE, Iosif AM, Schweitzer JB. A trial-by-trial analysis reveals more intense physical activity is associated with better cognitive control performance in attention-deficit/hyperactivity disorder.  Child Neuropsychol. 2016;22(5):618-26. doi: 10.1080/09297049.2015.1044511.

Hessl D, Sansone SM, Berry-Kravis E, Riley K, Widaman KF, Abbeduto L, Schneider A, Coleman J, Oaklander D, Rhodes KC, Gershon RC. The NIH Toolbox Cognitive Battery for intellectual disabilities: three preliminary studies and future directions.   J Neurodev Disord. 2016 Sep 6;8(1):35. doi: 10.1186/s11689-016-9167-4.

Horiuchi M, Smith L, Maezawa I, Jin LW. CX3CR1 ablation ameliorates motor and respiratory dysfunctions and improves survival of a Rett syndrome mouse model.   Brain Behav Immun. 2016 Feb 13. pii: S0889-1591(16)30035-6. doi: 10.1016/j.bbi.2016.02.014.

Jones KL, Croen LA, Yoshida CK, Heuer L, Hansen R, Zerbo O, DeLorenze GN, Kharrazi M, Yolken R, Ashwood P, Van de Water J. Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation.    Mol Psychiatry. 2016 May 24. doi: 10.1038/mp.2016.77.

Kazdoba TM, Leach PT, Yang M, Silverman JL, Solomon M, Crawley JN. Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.   Curr Top Behav Neurosci. 2016 Jun 16. [Epub ahead of print]

Kazdoba TM, Hagerman RJ, Zolkowska D, Rogawski MA, Crawley JN. Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism.   Psychopharmacology (Berl). 2016 Jan;233(2):309-23. doi: 10.1007/s00213-015-4115-7.

Kazdoba TM, Leach PT, Crawley JN. Behavioral phenotypes of genetic mouse models of autism.   Genes Brain Behav. 2016 Jan;15(1):7-26. doi: 10.1111/gbb.12256.

Klusek J, McGrath SE, Abbeduto L, Roberts JE. Pragmatic Language Features of Mothers With the FMR1 Premutation Are Associated With the Language Outcomes of Adolescents and Young Adults With Fragile X Syndrome.   J Speech Lang Hear Res. 2016 Feb 18:1-13. doi: 10.1044/2015_JSLHR-L-15-0102

Krakowiak P, Walker CK, Tancredi D, Hertz-Picciotto I, Van de Water J. Autism-specific maternal anti-fetal brain autoantibodies are associated with metabolic conditions.   Autism Res. 2016 Jun 17. doi: 10.1002/aur.1657.

Ku KM, Weir RK, Silverman JL, Berman RF, Bauman MD. Behavioral Phenotyping of Juvenile Long-Evans and Sprague-Dawley Rats: Implications for Preclinical Models of Autism Spectrum Disorders.   PLoS One. 2016 Jun 28;11(6):e0158150. doi: 10.1371/journal.pone.0158150. eCollection 2016.

Leach PT, Hayes J, Pride M, Silverman JL, Crawley JN. Normal Performance of Fmr1 Mice on a Touchscreen Delayed Nonmatching to Position Working Memory Task.   eNeuro. 2016 Mar 15;3(1). pii: ENEURO.0143-15.2016. doi: 10.1523/ENEURO.0143-15.2016.

Libero LE, Nordahl CW, Li DD, Ferrer E, Rogers SJ, Amaral DG. Persistence of megalencephaly in a subgroup of young boys with autism spectrum disorder.   Autism Res. 2016 Nov;9(11):1169-1182. doi: 10.1002/aur.1643.

Ligsay A, Hagerman RJ. Review of targeted treatments in fragile X syndrome.   Intractable Rare Dis Res. 2016 Aug;5(3):158-67. doi: 10.5582/irdr.2016.01045.

Loveall SJ, Channell MM, Phillips BA, Abbeduto L, Conners FA. Receptive vocabulary analysis in Down syndrome.   Res Dev Disabil. 2016 Apr 13;55:161-172. doi:10.1016/j.ridd.2016.03.018.

Matelski L, Van de Water J. Risk factors in autism: Thinking outside the brain. »  J Autoimmun. 2016 Feb;67:1-7. doi: 10.1016/j.jaut.2015.11.003.

McDuffie A, Machalicek W, Bullard L, Nelson S, Mello M, Tempero-Feigles R, Castignetti N, Abbeduto L. A Spoken-Language Intervention for School-Aged Boys With Fragile X Syndrome.   Am J Intellect Dev Disabil. 2016 May;121(3):236-265.

Muzar Z, Lozano R, Kolevzon A, Hagerman RJ. The neurobiology of the Prader-Willi phenotype of fragile X syndrome. Intractable Rare Dis Res. 2016 Nov;5(4):255-261.

Napoli E, Song G, Wong S, Hagerman R, Giulivi C. Altered Bioenergetics in Primary Dermal Fibroblasts from Adult Carriers of the FMR1 Premutation Before the Onset of the Neurodegenerative Disease Fragile X-Associated Tremor/Ataxia Syndrome.   Cerebellum. 2016 Apr 18.

Napoli E, Song G, Schneider A, Hagerman R, Eldeeb MA, Azarang A, Tassone F, Giulivi C. Warburg effect linked to cognitive-executive deficits in FMR1 premutation.   FASEB J. 2016 Oct;30(10):3334-3351. Epub 2016 Jun 22.

Nguyen CT, Krakowiak P, Hansen R, Hertz-Picciotto I, Angkustsiri K. Sociodemographic Disparities in Intervention Service Utilization in Families of Children with Autism Spectrum Disorder. J Autism Dev Disord. 2016 Dec;46(12):3729-3738.

Nordahl CW, Mello M, Shen AM, Shen MD, Vismara LA, Li D, Harrington K, Tanase C, Goodlin-Jones B, Rogers S, Abbeduto L, Amaral DG. Methods for acquiring MRI data in children with autism spectrum disorder and intellectual impairment without the use of sedation. J Neurodev Disord. 2016 May 5;8:20. doi: 10.1186/s11689-016-9154-9. eCollection 2016.

Ohta H, Nordahl CW, Iosif AM, Lee A, Rogers S, Amaral DG. Increased Surface Area, but not Cortical Thickness, in a Subset of Young Boys With Autism Spectrum Disorder.   Autism Res. 2016 Feb;9(2):232-48. doi: 10.1002/aur.1520.

Oswald TM, Beck JS, Iosif AM, McCauley JB, Gilhooly LJ, Matter JC, Solomon M. Clinical and Cognitive Characteristics Associated with Mathematics Problem Solving in Adolescents with Autism Spectrum Disorder.   Autism Res. 2016 Apr;9(4):480-90. doi: 10.1002/aur.1524.

Pearson BL, Crawley JN, Eilam D, Pentkowski NS, Summers CH. Curiosity as an approach to ethoexperimental analysis: behavioral neuroscience as seen by students and colleagues of Bob Blanchard.   Neurosci Biobehav Rev. 2016 Mar 24. pii: S0149-7634(15)30353-5. doi: 10.1016/j.neubiorev.2016.03.012.

Salcedo-Arellano MJ, Lozano R, Tassone F, Hagerman RJ, Saldarriaga W. Alcohol use dependence in fragile X syndrome.  Intractable Rare Dis Res. 2016 Aug;5(3):207-13. doi: 10.5582/irdr.2016.01046.

Saldarriaga W, Lein P, González Teshima LY, Isaza C, Rosa L, Polyak A, Hagerman R, Girirajan S, Silva M, Tassone F. Phenobarbital use and neurological problems in FMR1 premutation carriers.   Neurotoxicology 2016 Jan 21;53:141-147. doi: 10.1016/j.neuro.2016.01.008.

Schneider A, Johnston C, Tassone F, Sansone S, Hagerman RJ, Ferrer E, Rivera SM, Hessl D. Broad autism spectrum and obsessive-compulsive symptoms in adults with the fragile X premutation.   Clin Neuropsychol. 2016 Aug;30(6):929-43. doi: 10.1080/13854046.2016.1189536.

Schroeder DI, Schmidt RJ, Crary-Dooley FK, Walker CK, Ozonoff S, Tancredi DJ, Hertz-Picciotto I, LaSalle JM. Placental methylome analysis from a prospective autism study.   Mol Autism. 2016 Dec 15;7:51. doi: 10.1186/s13229-016-0114-8. eCollection 2016.

Scott JA, Goodrich-Hunsaker N, Kalish K, Lee A, Hunsaker MR, Schumann CM, Carmichael OT, Simon TJ. The hippocampi of children with chromosome 22q11.2 deletion syndrome have localized anterior alterations that predict severity of anxiety.  J Psychiatry Neurosci. 2016 Apr;41(3):203-13.

Seritan AL, Kim K, Benjamin I, Seritan I, Hagerman RJ. Risk Factors for Cognitive Impairment in Fragile X-Associated Tremor/Ataxia Syndrome.  J Geriatr Psychiatry Neurol. 2016 Sep 19. pii: 0891988716666379.

Shen MD, Li DD, Keown CL, Lee A, Johnson RT, Angkustsiri K, Rogers SJ, Müller RA, Amaral DG, Nordahl CW. Functional Connectivity of the Amygdala Is Disrupted in Preschool-Aged Children With Autism Spectrum Disorder.  J Am Acad Child Adolesc Psychiatry. 2016 Sep;55(9):817-24. doi: 10.1016/j.jaac.2016.05.020.

Schmidt RJ, Schroeder DI, Crary-Dooley FK, Barkoski JM, Tancredi DJ, Walker CK, Ozonoff S, Hertz-Picciotto I, LaSalle JM. Self-reported pregnancy exposures and placental DNA methylation in the MARBLES prospective autism sibling study.   Environ Epigenet. 2016 Dec;2(4). pii: dvw024. doi: 10.1093/eep/dvw024.

Schwartzer JJ, Careaga M, Coburn MA, Rose DR, Hughes HK, Ashwood P. Behavioral impact of maternal allergic-asthma in two genetically distinct mouse strains.  Brain Behav Immun. 2016 Sep 10. pii: S0889-1591(16)30416-0. doi: 10.1016/j.bbi.2016.09.007.

Solomon M, McCauley JB, Iosif AM, Carter CS, Ragland JD. Cognitive control and episodic memory in adolescents with autism spectrum disorders.   Neuropsychologia 2016 Aug.:31-41.

Song G, Napoli E, Wong S, Hagerman R, Liu S, Tassone F, Giulivi C. Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.   Mol Med. 2016 Jun 30;22. doi: 10.2119/molmed.2016.00122.

Sukoff Rizzo SJ, Silverman JL. Methodological Considerations for Optimizing and Validating Behavioral Assays.   Curr Protoc Mouse Biol. 2016 Dec 1;6(4):364-379. doi: 10.1002/cpmo.17.

Taylor SL, Ruhaak LR, Kelly K, Weiss RH, Kim K. Effects of imputation on correlation: implications for analysis of mass spectrometry data from multiple biological matrices.  Brief Bioinform. 2016 Feb 19. pii: bbw010.

Taylor SL, Ruhaak LR, Weiss RH, Kelly K, Kim K. Multivariate Two-part Statistics for Analysis of Correlated Mass Spectrometry Data from multiple Biological Specimens.   Bioinformatics. 2016 Sep 4. pii: btw578.

Wong, S., Napoli, E., Krakowiak, P., Tassone, F., Hertz-Picciotto, I., & Giulivi, C. Role of p53, Mitochondrial DNA Deletions, and Paternal Age in Autism: A Case-Control Study.   Pediatrics, 137(4), peds-2015.

2015

Akintunde ME.,Rose M., Krakowiak P., Heuer L., Ashwood P., Hansen R., Hertz-Picciotto I., Van de Water J. Increased production of IL-17 in children with autism spectrum disorders and co-morbid asthma. Neuroimmunol. 2015 Sep 15;286:33-41. doi: 10.1016/j.jneuroim.2015.07.003.

Ander BP, Barger N, Stamova B, Sharp FR, Schumann CM. Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders. Mol Autism. 2015 Jun 19;6:37. doi: 10.1186/s13229-015-0029-9.

Benjamin, D.P., McDuffie, A., Thurman, A., Kover, S.T., Mastergeorge, A., Hagerman, R.J., & Abbeduto, L. Effect of speaker gaze on word learning in fragile X syndrome: A comparison with nonsyndromic ASD.  Journal of Speech, Language, and Hearing Research. PMID: 25629603.

Channell MM, McDuffie AS, Bullard LM, Abbeduto L. Narrative language competence in children and adolescents with Down syndrome. Front Behav Neurosci. 2015 Oct 30;9:283.

Flannery BM, Silverman JL, Bruun DA, Puhger KR, Crawley JN, Lein PJ. Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine.  Neurotox Teratol 47:36-45. PMID: 25446016

Fox-Edmiston E, Van de Water J. Maternal Anti-Fetal Brain IgG Autoantibodies and Autism Spectrum Disorder: Current Knowledge and its Implications for Potential Therapeutics.  CNS Drugs. 2015 Sep 14.PMID: 26369920

Grodzki, ACG, Poola B, Pasupuleti N, Nantz MH, Lein PJ, Gorin FA. The novel carboline derivative, 6-chloro-8-(glycinil) amino-β-carboline, inhibits nitric oxide formation independent of effects on TNFα and Il-1β expression in macrophages. J Pharmacol Exp Therap 352(3):438-47. PMID: 25538105

Hagerman RJ, Polussa J. Treatment of the psychiatric problems associated with fragile X syndrome. Curr Opin Psychiatry. 2015 Mar;28(2):107-12. doi: 10.1097/YCO.0000000000000131.

Harrill JA, Chen H, Streifel K, Yang D, Mundy WR, Lein PJ. Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical cells.  Mol Brain. 2015 Feb 15;8:10. doi: 10.1186/s13041-015-0099-9.

Jin LW, Horiuchi M, Wulff H, Liu XB, Cortopassi GA, Erickson JD, Maezawa I. Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity.  J Neurosci. 2015 Feb 11;35(6):2516-29. doi: 10.1523/JNEUROSCI.2778-14.2015.

Krakowiak P, Goines PE, Tancredi DJ, Ashwood P, Hansen RL, Hertz-Picciotto I, Van de Water J. Neonatal Cytokine Profiles Associated with Autism Spectrum Disorder.  Biol Psychiatry. 2015 Aug 14. pii: S0006-3223(15)00655-1. doi: 10.1016/j.biopsych.2015.08.007.

Miller M, Iosif AM, Young GS, Hill M, Phelps Hanzel E, Hutman T, Johnson S, Ozonoff S. School-age outcomes of infants at risk for autism spectrum disorder.  Autism Res. 2015 Oct 9. doi: 10.1002/aur.1572

Nordahl CW, Iosif, AM, Young GS, Perry LM, Dougherty R, Lee A, Li D, Buonocore MH, Simon TJ, Rogers SJ, Wandell B, Amaral DG. Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder.   Mol Autism. 2015 May 13;6:26. doi: 10.1186/s13229-015-0005-4.

Oakes A, Thurman AJ, McDuffie A, Bullard LM, Hagerman RJ, Abbeduto L. Characterising repetitive behaviours in young boys with fragile X syndrome. J Intellect Disabil Res. 2015 Oct 8. doi: 10.1111/jir.12234.

Pasupuleti N, Grodzki AC, Gorin F. Mis-trafficking of endosomal urokinase proteins triggers drug-induced glioma nonapoptotic cell death.  Mol Pharmacol 87(4):683-96.

Philippat C, Bennett DH, Krakowiak P, Rose M, Hwang HM, Hertz-Picciotto I. Phthalate concentrations in house dust in relation to autism spectrum disorder and developmental delay in the CHildhood Autism Risks from Genetics and the Environment (CHARGE) study.  Environ Health. 2015 Jun 26;14:56. doi: 10.1186/s12940-015-0024-9.

Silverman JL, Pride MC, Hayes JE, Puhger KR, Butler-Struben HM, Baker S, Crawley JN. GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism. Neuropsychopharmacology. 2015 Aug;40(9):2228-39. doi: 10.1038/npp.2015.66.

Solomon M, Ragland JD, Niendam TA, Lesh TA, Beck JS, Matter JC, Frank MJ, Carter CS. Atypical Learning in Autism Spectrum Disorders: A Functional Magnetic Resonance Imaging Study of Transitive Inference. J Am Acad Child Adolesc Psychiatry. 2015 Nov;54(11):947-55. doi: 10.1016/j.jaac.2015.08.010.

Thurman AJ, McDuffie A, Kover ST, Hagerman R, Channell MM, Mastergeorge A, Abbeduto L. Use of emotional cues for lexical learning: a comparison of autism spectrum disorder and fragile X syndrome.   J Autism Dev Disord. 2015 Apr;45(4):1042-61. doi: 10.1007/s10803-014-2260-1.

Thurman AJ, McDuffie A, Kover ST, Hagerman RJ, Abbeduto L. Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder. J Autism Dev Disord. PMID: 25904201

Walker CK, Krakowiak P, Baker A, Hansen RL, Ozonoff S, Hertz-Picciotto I. Preeclampsia, placental insufficiency, and autism spectrum disorder or developmental delay.  JAMA Pediatr. 2015 Feb;169(2):154-62. doi:10.1001/jamapediatrics.2014.2645.

Walker CK, Ashwood P, Hertz-Picciotto I. Preeclampsia, placental insufficiency, autism, and antiphospholipid antibodies-reply. JAMA Pediatr. 2015 Jun;169(6):606-7. doi: 10.1001/jamapediatrics.2015.0345.

Winarni TI, Schneider A, Ghaziuddin N, Seritan A, Hagerman RJ. Psychosis and catatonia in fragile X: Case report and literature review. Intractable Rare Dis Res. 2015 Aug;4(3):139-46. doi: 10.5582/irdr.2015.01028..

2014

Abbeduto, L, McDuffie, A, & Thurman, AJ.  The fragile X syndrome-autism comorbidity: what do we really know? Frontiers in Genetics, October, doi: 10.3389/fgene.2014.00355.

Bales KL, M Solomon, S Jacob, JN Crawley, JL Silverman, RH Larke, E Sahagunl, KR Puhger, MC Pride and SP Mendoza. Long-term exposure to intranasal oxytocin in a mouse autism model.  Translational Psychiatry (2014) 4, e480; doi:10.1038/tp.2014.117.

Benjamin DP, Mastergeorge AM, McDuffie AS, Kover ST, Hagerman RJ, Abbeduto L.  Effects of labeling and pointing on object gaze in boys with fragile X syndrome: An eye-tracking study. Res Dev Disabil. 35(11):2658-72. doi: 10.1016/j.ridd.2014.06.021.

Channell MM, Thurman AJ, Kover ST, Abbeduto L.  Patterns of change in nonverbal cognition in adolescents with Down syndrome. Res Dev Disabil. 35(11):2933-41. doi: 10.1016/j.ridd.2014.07.014.

Hauser CT, Kover ST, Abbeduto L. Maternal well-being and child behavior in families with fragile X syndrome. Res Dev Disabil. 2014 Oct;35(10):2477-86. doi: 10.1016/j.ridd.2014.06.012.

Klusek J., Roberts JE., Losh M. Cardiac autonomic regulation in autism and Fragile X syndrome: a review. Psychol Bull. 2015 Jan;141(1):141-75. doi: 10.1037/a0038237. Epub 2014 Nov 24. PMID: 25420222

Kover ST, Haebig E, Oakes A, McDuffie A, Hagerman RJ, Abbeduto L. Sentence comprehension in boys with autism spectrum disorder. Am J Speech Lang Pathol. 2014 Aug;23(3):385-94. doi: 10.1044/2014_AJSLP-13-0073.