Angela Haczku, M.D., Ph.D.
Director, UC Davis Lung Center
Professor of Medicine
Specialties
Allergology
Immunology
Respiratory pathology and physiology
Pulmonary and Critical Care
Department
Locations and Contact
UC Davis Medical Center
UC Davis Medical Center
2315 Stockton Blvd.
Sacramento, CA 95817
Phone: 800-2-UCDAVIS (800-282-3284)
Clinical Interests
Dr. Haczku is an internationally recognized expert in pulmonary immunology. She studies the effects of environmental exposures (allergens, air pollution, cigarette smoke and psychosocial stress) on respiratory health and disease. She is interested in how the epithelium and local immune cells cooperate in maintaining a healthy lung tissue. More recently her team has been focusing on COVID-19 immunity and the effects of climate change on respiratory health. She has been federally funded for the past 20 years and has received numerous awards, such as the Parker B Francis Pulmonary Fellowship, the MRC (Canada) Fellowship Award and the American Lung Association (ALA) Career Investigator Award. At UC Davis, she holds the Chester Robbins Endowment for Pulmonary Research. Dr. Haczku is a Fellow of the American Academy of Asthma, Allergy and Immunology (AAAAI), and is an inducted member of the Collegium Internationale Allergologicum. She has served on expert panels of the American Lung Association, American Thoracic Society (ATS), National Institutes of Health, Veterans Health Administration, Department of Defense and numerous European and global agencies. She is the elected Chair of the AAAAI Mechanisms of Allergy and Immunology Interest Section and was the elected Chair of the ATS Allergy, Inflammation and Immunology Program Committee. She has been associate editor of Respiratory Research; Allergy; The International Archives of Allergy and Immunology; and served on the editorial boards of the Journal of Allergy and Clinical Immunology, the American Journal of Respiratory Cell and Molecular Biology, and the American Journal of Physiology, among others. She trained numerous undergraduate and graduate students and postdoctoral and clinical fellows who remain in research positions all over the world; several became full professors, directing their own research programs.
Research/Academic Interests
Dr. Haczku is a respiratory immunologist with a research focus on the pathogenesis of allergy, asthma, COPD and pulmonary infections. She is interested in studying the effects of environmental exposures such as air pollution, cigarette smoking and psychosocial stress on airway inflammation. She has developed in vivo (animal) and in vitro models to investigate disease mechanisms and treatment. Dr. Haczku currently serves as associate dean for translational research for the UC Davis School of Medicine.
Division
Medical School
M.D., University Medical School of Debrecen, Debrecen, Hungary 1986
Other School
Ph.D., Immunology, Imperial College, London, UK 1997
Internship
Internal Medicine, University Medical School of Debrecen, Debrecen, Hungary 1985-1986
Residency
Internal and Pulmonary Medicine, University Medical School of Debrecen, Debrecen, Hungary 1986-1990
Fellowship
Postdoctoral Fellowship-Allergy and Clinical Immunology, National Jewish Medical and Research Center, Denver CO 1995-1998
Chair, Interest Sections Coordinating Committee, AAAAI, 2021
Elected Chair, Mechanisms of Asthma, Allergy and Immunology Interest Section, AAAAI, 2019
Associate Dean of Research, UC Davis School of Medicine, 2019
Elected Chair, Asthma, Inflammation and Immunity Assembly Program Committee, American Thoracic Society (ATS), 2014
Joan Ottinger Memorial Award for Outstanding Research in Cancer or Lung Disease (UC Davis), 2018
Chester Robbins Pulmonary Research Endowment (UC Davis), 2018
Inducted Member, Collegium Internationale Allergologicum, 2016
Elected Fellow, American Academy of Asthma, Allergy, and Immunology, 2008
Career Investigator Award, American Lung Association, 2008
Research Award, American Lung Association, 2003
Parker B. Francis Pulmonary Research Fellowship, Francis Families Foundation, 2000
MRC Fellowship Award (Medical Research Council of Canada; Ranked 3 of 170), 1999
Fellowship Award, International Life Sciences Institute, 1997
Pharmacia Allergy Fellowship, Pharmacia Allergy Foundation, 1997
First Place Von Pirquet Prize, American College of Asthma, Allergy, and Immunology, 1996
To view Dr. haczku's publications, please click here.
I-SPY COVID Consortium. Clinical trial design during and beyond the pandemic: the I-SPY COVID trial. Nat Med. 2022 Jan;28(1):9-11. doi:10.1038/s41591-021-01617-x. PMID:35058620.
Georas SN, Wright RJ, Ivanova A, Israel E, LaVange LM, Akuthota P, Carr TF, Denlinger LC, Fajt ML, Kumar R, O'Neal WK, Phipatanakul W, Szefler SJ, Aronica MA, Bacharier LB, Burbank AJ, Castro M, Crotty Alexander L, Bamdad J, Cardet JC, Comhair SAA, Covar RA, DiMango EA, Erwin K, Erzurum SC, Fahy JV, Gaffin JM, Gaston B, Gerald LB, Hoffman EA, Holguin F, Jackson DJ, James J, Jarjour NN, Kenyon NJ, Khatri S, Kirwan JP, Kraft M, Krishnan JA, Liu AH, Liu MC, Marquis MA, Martinez F, Mey J, Moore WC, Moy JN, Ortega VE, Peden DB, Pennington E, Peters MC, Ross K, Sanchez M, Smith LJ, Sorkness RL, Wechsler ME, Wenzel SE, White SR, Zein J, Zeki AA, Noel P; PrecISE Study Team. The Precision Interventions for Severe and/or Exacerbation-Prone (PrecISE) Asthma Network: An overview of Network organization, procedures, and interventions. J Allergy Clin Immunol. 2022 Feb;149(2):488-516.e9. doi:10.1016/j.jaci.2021.10.035. Epub 2021 Nov 29. PMID:34848210.
Hernandez P, Kim D, Haczku A. The Flying Monkeys of Ozone: Oxysterols Inactivate NLRP2 in Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2021 Nov;65(5):461-463. doi:10.1165/rcmb.2021-0275ED. PMID:34375162.
Coil DA, Albertson T, Banerjee S, Brennan G, Campbell AJ, Cohen SH, Dandekar S, Díaz-Muñoz SL, Eisen JA, Goldstein T, Jose IR, Juarez M, Robinson BA, Rothenburg S, Sandrock C, Stoian AMM, Tompkins DG, Tremeau-Bravard A, Haczku A. SARS-CoV-2 detection and genomic sequencing from hospital surface samples collected at UC Davis. PLoS One. 2021 Jun 24;16(6):e0253578. doi:10.1371/journal.pone.0253578. eCollection 2021. PMID:34166421
Enweasor C, Flayer CH, Haczku A. Ozone-Induced Oxidative Stress, Neutrophilic Airway Inflammation, and Glucocorticoid Resistance in Asthma. Front Immunol. 2021 Feb 26;12:631092. doi:10.3389/fimmu.2021.631092. eCollection 2021. PMID:33717165.
Irani C, Haczku A. Grains of Wisdom: Transgenic Rice for Oral Allergen Immunotherapy in Japanese Cedar Pollen-Allergic Patients. Int Arch Allergy Immunol. 2021;182(2):106-108. doi:10.1159/000513627. Epub 2020 Dec 15. PMID:33321507.
Adegunsoye A, Alqalyoobi S, Linderholm A, Bowman WS, Lee CT, Pugashetti JV, Sarma N, Ma SF, Haczku A, Sperling A, Strek ME, Noth I, Oldham JM. Circulating Plasma Biomarkers of Survival in Antifibrotic-Treated Patients With Idiopathic Pulmonary Fibrosis. Chest. 2020 Oct;158(4):1526-1534. doi:10.1016/j.chest.2020.04.066. Epub 2020 May 22. PMID:32450241.
Sanville B, Corbett R, Pidcock W, Hardin K, Sebat C, Nguyen MV, Thompson GR, Haczku A, Schivo M, Cohen S. A Community-transmitted Case of Severe Acute Respiratory Distress Syndrome (SARS) Due to SARS-CoV-2 in the United States. Clin Infect Dis. 2020 Nov 19;71(16):2222-2226. doi:10.1093/cid/ciaa347. PMID:32227197.
Flayer CH, Larson ED, Joseph A, Kao S, Qu W, Van Haren A, Royer CM, Miller LA, Capitanio JP, Sielecki T, Christofidou-Solomidou M, Haczku A. Ozone-induced enhancement of airway hyperreactivity in rhesus macaques: Effects of antioxidant treatment. J Allergy Clin Immunol. 2020 Jan;145(1):312-323. doi:10.1016/j.jaci.2019.08.034. Epub 2019 Oct 15. PMID:31627909.