Services

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  • Basic standardized service - The Immune Modeling, Analysis, and Diagnostics Shared Resource, or IMADSR, offers immune cell profiling via flow cytometry including intracellular cytokine detection and cell surface phenotyping. Multiplex analyte detection (Luminex-based multiplex assays), immune cellular assays (CFSE dilution, antigen-specific and non-specific responses and cytokine production), and gene expression profiling (Illumina-based whole transcriptome sequencing, qRT-PCR arrays, etc.) are also available. Affordability is a priority for all services provided.
  • Single cell sequencing - The IMADSR offers state-of-the-art single cell sequencing services including REAP-Seq, CITE-Seq, targeted scRNA-Seq, and scTCR/BCR-seq.  The IMADSR is also skilled at isolating cells from various sources (e.g. skin, tumor, and intestine). All analysis is performed in-house.
  • Banking service - The IMADSR offers patient specimen processing and storage using electronic sample management and tracking systems. Sample acquisition, isolation, storage and distribution are performed according to verified and validated standard SOPs, which provide consistent processes for all research activities from sample to sample, investigator to investigator, and study to study. Peripheral blood is ideal for immune monitoring; however, the IMADSR  has established protocols for sample processing obtained from other sources such as skin, tumor, saliva and urine. Large reliable data stores protect all information.
  • Murine models of autoimmunity and cancer - The IMADSR provides individual consultation on experimental design and appropriate sample collection for analysis. The shared resource provides expert advice for optimal project-specific immunologic assessment and innovative approaches to evaluate immune responses in clinical studies.
  • Consulting service - The IMADSR provides individual consultation on experimental design and appropriate sample collection for analysis. The shared resource provides expert advice for optimal project-specific immunologic assessment and innovative approaches to evaluate immune responses in clinical studies.
  • Diagnostic tests - The IMADSR is a CLIA certified laboratory which offers diagnostic tests such as TCR and BCR rearrangement studies.